2. Gene
  3. Ucn - urocortin Gene

Ucn - urocortin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29151 | 基因类型: protein coding

关于 Ucn

功能概要

Enables corticotropin-releasing hormone receptor 1 binding activity; corticotropin-releasing hormone receptor 2 binding activity; and histone deacetylase inhibitor activity. Involved in several processes, including negative regulation of cell death; positive regulation of macromolecule metabolic process; and regulation of secretion. Located in axon; dendrite; and perikaryon. Used to study Parkinsonism and thromboangiitis obliterans. Biomarker of asthma; colitis; and thromboangiitis obliterans. Orthologous to human UCN (urocortin). [provided by Alliance of Genome Resources, Apr 2022]

Ucn 基因产物(1)

mRNA Protein Name
NM_019150.2 NP_062023.1 urocortin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor binding IDA
IDA: 通过直接分析推断
11784785 RGD
enables corticotropin-releasing hormone receptor 1 binding IPI
IPI: 通过物理相互作用推断
15049707 RGD
enables corticotropin-releasing hormone receptor 2 binding IPI
IPI: 通过物理相互作用推断
7477349 RGD
enables histone deacetylase inhibitor activity IDA
IDA: 通过直接分析推断
19875195 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
7477349 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in activation of protein kinase A activity IDA
IDA: 通过直接分析推断
19460778 RGD
involved in aerobic respiration IDA
IDA: 通过直接分析推断
11597609 RGD
involved in associative learning IDA
IDA: 通过直接分析推断
10366634 RGD
involved in drinking behavior IMP
IMP: 通过突变表型推断
10751559 RGD
involved in feeding behavior IMP
IMP: 通过突变表型推断
10751559 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
17391780 RGD
involved in learning or memory IDA
IDA: 通过直接分析推断
12376180 RGD
involved in negative regulation of apoptotic process IDA
IDA: 通过直接分析推断
14519439 RGD
involved in negative regulation of appetite IDA
IDA: 通过直接分析推断
21540451 RGD
involved in negative regulation of blood pressure IDA
IDA: 通过直接分析推断
15604589 RGD
involved in negative regulation of cell size IDA
IDA: 通过直接分析推断
19460778 RGD
involved in negative regulation of feeding behavior IDA
IDA: 通过直接分析推断
11597609 RGD
involved in negative regulation of gene expression IDA
IDA: 通过直接分析推断
14563694 RGD
involved in negative regulation of hormone secretion IDA
IDA: 通过直接分析推断
21540451 RGD
involved in negative regulation of neuron apoptotic process IDA
IDA: 通过直接分析推断
11784785 RGD
involved in neuron projection development IDA
IDA: 通过直接分析推断
15078549 RGD
involved in neuropeptide signaling pathway IDA
IDA: 通过直接分析推断
11784785 RGD
involved in positive regulation of DNA replication IDA
IDA: 通过直接分析推断
11087261 RGD
involved in positive regulation of behavioral fear response IDA
IDA: 通过直接分析推断
10366634 RGD
involved in positive regulation of cAMP/PKA signal transduction IDA
IDA: 通过直接分析推断
7477349 RGD
involved in positive regulation of calcium ion import IDA
IDA: 通过直接分析推断
16513211 RGD
involved in positive regulation of cardiac muscle contraction IDA
IDA: 通过直接分析推断
19460778 RGD
involved in positive regulation of cell growth IDA
IDA: 通过直接分析推断
15694367 RGD
involved in positive regulation of collagen biosynthetic process IDA
IDA: 通过直接分析推断
11087261 RGD
involved in positive regulation of corticotropin secretion IDA
IDA: 通过直接分析推断
7477349 RGD
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
21540451 RGD
involved in positive regulation of interleukin-6 production IDA
IDA: 通过直接分析推断
12746280 RGD
involved in positive regulation of peptidyl-serine phosphorylation IDA
IDA: 通过直接分析推断
19875195 RGD
involved in positive regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
14519439 RGD
involved in positive regulation of translation IDA
IDA: 通过直接分析推断
11087261 RGD
involved in positive regulation of vascular permeability IDA
IDA: 通过直接分析推断
19819946 RGD
involved in regulation of synaptic transmission, glutamatergic IDA
IDA: 通过直接分析推断
15102917 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
16672665 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
16427607 RGD
involved in response to oxidative stress IDA
IDA: 通过直接分析推断
11784785 RGD
involved in response to pain IEP
IEP: 通过表达模式推断
21463663 RGD
involved in social behavior IDA
IDA: 通过直接分析推断
16488545 RGD
involved in vasodilation IDA
IDA: 通过直接分析推断
15467262 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
12379245 RGD
located in axon terminus IDA
IDA: 通过直接分析推断
12379245 RGD
located in dendrite IDA
IDA: 通过直接分析推断
12379245 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
12379245 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
10553117 RGD
located in varicosity IDA
IDA: 通过直接分析推断
15796765 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

urocortin

corticotensin

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-13661 7-Hydroxystaurosporine / Phase 2
Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P1858A Urocortin III, mouse TFA Activator 95.93% 否
HY-105416 Calphostin C Inhibitor 99.00% 否
HY-108262 UCN-02 Inhibitor ≥98.0% 否
HY-P1858 Urocortin III, mouse Activator / 否
HY-RS15407 UCN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS15408 UCN2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS15409 UCN3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17732 Ucn Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21451 Ucn3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24197 Ucn Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27969 Ucn3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ucn NCBI NCBI:7349
Mus musculus Ucn NCBI NCBI:22226
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