2. Gene
  3. Homer1 - homer scaffold protein 1 Gene

Homer1 - homer scaffold protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Vesl-1; HOMER1F

基因 ID: 29546 | 基因类型: protein coding

关于 Homer1

功能概要

Enables several functions, including identical protein binding activity; scaffold protein binding activity; and type 5 metabotropic glutamate receptor binding activity. A structural constituent of postsynapse. Involved in several processes, including G protein-coupled glutamate receptor signaling pathway; protein tetramerization; and regulation of dendritic spine maintenance. Located in dendritic shaft; dendritic spine; and neuronal cell body. Is active in glutamatergic synapse and postsynaptic density. Colocalizes with excitatory synapse. Orthologous to human HOMER1 (homer scaffold protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Homer1 基因产物(1)

mRNA Protein Name
NM_031707.2 NP_113895.1 homer protein homolog 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled glutamate receptor binding IPI
IPI: 通过物理相互作用推断
15758184 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
19345194 RGD
enables molecular adaptor activity IPI
IPI: 通过物理相互作用推断
10433269 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9069287 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
9727012 RGD
enables scaffold protein binding IPI
IPI: 通过物理相互作用推断
10433269 RGD
enables signaling receptor binding IDA
IDA: 通过直接分析推断
9069287 RGD
enables structural constituent of postsynapse IDA
IDA: 通过直接分析推断
17880892 RGD
enables structural constituent of postsynapse IMP
IMP: 通过突变表型推断
17880892 RGD
enables type 5 metabotropic glutamate receptor binding IPI
IPI: 通过物理相互作用推断
16554037 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled glutamate receptor signaling pathway IDA
IDA: 通过直接分析推断
9069287 RGD
involved in circadian rhythm IEP
IEP: 通过表达模式推断
15308308 RGD
involved in protein localization to synapse IDA
IDA: 通过直接分析推断
12867517 RGD
involved in protein tetramerization IDA
IDA: 通过直接分析推断
19345194 RGD
involved in regulation of dendritic spine maintenance IMP
IMP: 通过突变表型推断
19345194 RGD
involved in regulation of synaptic transmission, glutamatergic IMP
IMP: 通过突变表型推断
19345194 RGD
involved in response to cocaine IEP
IEP: 通过表达模式推断
18932227 RGD
involved in response to nicotine IEP
IEP: 通过表达模式推断
15813924 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendrite IDA
IDA: 通过直接分析推断
16554037 RGD
located in dendritic shaft IDA
IDA: 通过直接分析推断
9069287 RGD
located in dendritic spine IDA
IDA: 通过直接分析推断
30021165 RGD
located in excitatory synapse IDA
IDA: 通过直接分析推断
9069287 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
10433269 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
17880892 RGD
located in neuron spine IDA
IDA: 通过直接分析推断
19345194 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
9069287 RGD
is active in postsynaptic density IDA
IDA: 通过直接分析推断
10433269 RGD
located in postsynaptic density IDA
IDA: 通过直接分析推断
10433269 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

homer protein homolog 1

PSD-Zip45

VASP/Ena-related gene up-regulated during seizure and LTP 1

homer homolog 1

homer scaffolding protein 1

homer, neuronal immediate early gene, 1

scaffold protein

Homer1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Homer1 Q9Z214 Grm5 Mus musculus Q3UVX5
NMR
23911326
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06283 HOMER1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21139 Homer1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27657 Homer1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Homer1 NCBI NCBI:9456
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