2. Gene
  3. Pdha1 - pyruvate dehydrogenase E1 subunit alpha 1 Gene

Pdha1 - pyruvate dehydrogenase E1 subunit alpha 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29554 | 基因类型: protein coding

关于 Pdha1

功能概要

Enables pyruvate dehydrogenase (acetyl-transferring) activity. Involved in acetyl-CoA biosynthetic process from pyruvate. Located in mitochondrion. Part of pyruvate dehydrogenase complex. Used to study pyruvate decarboxylase deficiency. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human PDHA1 (pyruvate dehydrogenase E1 subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Pdha1 基因产物(1)

mRNA Protein Name
NM_001004072.2 NP_001004072.2 pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables pyruvate dehydrogenase (acetyl-transferring) activity IDA
IDA: 通过直接分析推断
7487891 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acetyl-CoA biosynthetic process from pyruvate IDA
IDA: 通过直接分析推断
7487891 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of pyruvate dehydrogenase complex IDA
IDA: 通过直接分析推断
7487891 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

PDHE1-A type I

pyruvate dehydrogenase (lipoamide) alpha 1

pyruvate dehydrogenase E1 alpha 1 subunit

pyruvate dehydrogenase E1alpha subunit

pyruvate dehydrogenase alpha 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10261 PDHA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17710 Pdha1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24175 Pdha1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pdha1 NCBI NCBI:5160
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