2. Gene
  3. Pecam1 - platelet and endothelial cell adhesion molecule 1 Gene

Pecam1 - platelet and endothelial cell adhesion molecule 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: CD31; Pecam

基因 ID: 29583 | 基因类型: protein coding

关于 Pecam1

功能概要

Enables protein Phosphatase binding activity. Involved in several processes, including cellular response to interferon-gamma; negative regulation of GTPase activity; and negative regulation of actin filament polymerization. Located in cell surface and ruffle. Used to study pulmonary hypertension. Biomarker of Bacterial pneumonia; orchitis; and osteoarthritis. Human ortholog(s) of this gene implicated in coronary artery disease (multiple); lung non-small cell carcinoma; neuroblastoma; and psoriatic arthritis. Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Pecam1 基因产物(1)

mRNA Protein Name
NM_031591.2 NP_113779.1 platelet endothelial cell adhesion molecule precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein phosphatase binding IPI
IPI: 通过物理相互作用推断
9388260 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
21414398 RGD
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: 通过表达模式推断
18466611 RGD
involved in cellular response to type II interferon IEP
IEP: 通过表达模式推断
18466611 RGD
involved in negative regulation of GTPase activity IDA
IDA: 通过直接分析推断
17662049 RGD
involved in negative regulation of actin filament polymerization IDA
IDA: 通过直接分析推断
17662049 RGD
involved in negative regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
17662049 RGD
involved in positive regulation of cellular extravasation IMP
IMP: 通过突变表型推断
10861081 RGD
involved in positive regulation of leukocyte migration IMP
IMP: 通过突变表型推断
8248808 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
18466611 RGD
located in ruffle IDA
IDA: 通过直接分析推断
9148965 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

platelet endothelial cell adhesion molecule

PECAM-1

platelet/endothelial cell adhesion molecule 1

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P3444 CD31 99.33% 否
HY-P3444A CD31 TFA / 否
HY-RS10315 PECAM1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17929 Pecam1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24399 Pecam1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990277 Anti-Mouse CD31/PECAM-1 Antibody (390) Inhibitor ≥95.0% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pecam1 NCBI NCBI:5175
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z