Mad2l1 - mitotic arrest deficient 2 like 1 Gene

种属: Rattus norvegicus

关于 Mad2l1

功能概要

Predicted to enable protein C-terminus binding activity and protein homodimerization activity. Predicted to be involved in several processes, including establishment of centrosome localization; negative regulation of protein metabolic process; and regulation of mitotic metaphase/anaphase transition. Predicted to act upstream of or within mitotic sister chromatid segregation and negative regulation of mitotic cell cycle. Predicted to be located in several cellular components, including chromosome, centromeric region; perinuclear region of cytoplasm; and spindle. Predicted to be part of nuclear pore nuclear basket. Predicted to be active in cytoplasm; kinetochore; and nucleoplasm. Orthologous to human MAD2L1 (mitotic arrest deficient 2 like 1). [provided by Alliance of Genome Resources, Apr 2022]