1. Gene
  2. Gfpt1 - glutamine fructose-6-phosphate transaminase 1 Gene

Gfpt1 - glutamine fructose-6-phosphate transaminase 1 Gene

种属: Rattus norvegicus

同用名: GFA; GFAT; Gfpt; GFAT1; GFAT1m

基因 ID: 297417 | 基因类型: protein coding

关于 Gfpt1

功能概要

Enables several functions, including amino acid binding activity; glutamine-fructose-6-phosphate transaminase (isomerizing) activity; and identical protein binding activity. Involved in several processes, including fructose 6-phosphate metabolic process; glucosamine biosynthetic process; and negative regulation of glycogen biosynthetic process. Biomarker of familial hyperlipidemia and hyperinsulinism. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 12 and obesity. Orthologous to human GFPT1 (glutamine--fructose-6-phosphate transaminase 1). [provided by Alliance of Genome Resources, Apr 2022]

Gfpt1 基因产物(1)

mRNA Protein Name
NM_001005879.1 NP_001005879.1 glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables amino acid binding IDA
IDA: 通过直接分析推断
10898949 RGD
enables carbohydrate binding IDA
IDA: 通过直接分析推断
10898949 RGD
enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity IDA
IDA: 通过直接分析推断
10898949 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
10898949 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in UDP-N-acetylglucosamine metabolic process IMP
IMP: 通过突变表型推断
10898949 RGD
involved in cellular response to insulin stimulus IEP
IEP: 通过表达模式推断
10604279 RGD
involved in fructose 6-phosphate metabolic process IDA
IDA: 通过直接分析推断
10898949 RGD
involved in glucosamine biosynthetic process IDA
IDA: 通过直接分析推断
10898949 RGD
involved in negative regulation of glycogen biosynthetic process IMP
IMP: 通过突变表型推断
8349040 RGD
involved in response to insulin IEP
IEP: 通过表达模式推断
7589852 RGD
involved in response to sucrose IEP
IEP: 通过表达模式推断
16555472 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1

D-fructose-6-phosphate amidotransferase 1

GFAT 1

glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1

glutamine:fructose-6-phosphate amidotransferase 1

hexosephosphate aminotransferase 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gfpt1 NCBI NCBI:2673