2. Gene
  3. Kcnq4 - potassium voltage-gated channel subfamily Q member 4 Gene

Kcnq4 - potassium voltage-gated channel subfamily Q member 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 298496 | 基因类型: protein coding

关于 Kcnq4

功能概要

Enables Potassium Channel activity. Involved in negative regulation of dopaminergic synaptic transmission; potassium ion transport; and sensory perception of sound. Located in cytoplasm; neuron projection; and plasma membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 2A and sensorineural hearing loss. Orthologous to human KCNQ4 (potassium voltage-gated channel subfamily Q member 4). [provided by Alliance of Genome Resources, Apr 2022]

Kcnq4 基因产物(6)

mRNA Protein Name
XM_039111224.1 XP_038967152.1 potassium voltage-gated channel subfamily KQT member 4 isoform X2
XM_008764110.3 XP_008762332.1 potassium voltage-gated channel subfamily KQT member 4 isoform X4
XM_039111225.1 XP_038967153.1 potassium voltage-gated channel subfamily KQT member 4 isoform X3
XM_008764109.2 XP_008762331.1 potassium voltage-gated channel subfamily KQT member 4 isoform X1
XM_008764111.3 XP_008762333.1 potassium voltage-gated channel subfamily KQT member 4 isoform X5
XM_039111226.1 XP_038967154.1 potassium voltage-gated channel subfamily KQT member 4 isoform X6
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables potassium channel activity IDA
IDA: 通过直接分析推断
17021181 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of synaptic transmission, dopaminergic IMP
IMP: 通过突变表型推断
16775195 RGD
involved in potassium ion transport IDA
IDA: 通过直接分析推断
17021181 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

potassium voltage-gated channel subfamily KQT member 4

KQT-like 4

potassium channel subunit alpha KvLQT4

potassium channel, voltage-gated KQT-like subfamily Q, member 4

potassium voltage-gated channel, KQT-like subfamily, member 4

voltage-gated potassium channel subunit Kv7.4

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-122114 ICA-27243 Activator 99.27% 否
HY-18063 ML252 Inhibitor 99.9% 否
HY-123264 RL648_81 Inhibitor 99.20% 否
HY-RS07176 KCNQ4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-115823 ztz240 / 否
HY-18063A ML252 hydrochloride Inhibitor / 否
HY-RS18392 Kcnq4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24873 Kcnq4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kcnq4 NCBI NCBI:9132
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