2. Gene
  3. Brf1 - BRF1, RNA polymerase III transcription initiation factor subunit Gene

Brf1 - BRF1, RNA polymerase III transcription initiation factor subunit Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 299347 | 基因类型: protein coding

关于 Brf1

功能概要

Predicted to enable RNA polymerase III general transcription initiation factor activity and RNA polymerase III type 3 promoter sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase III. Predicted to be part of transcription factor TFIIIB complex and transcription preinitiation complex. Predicted to be active in nucleus. Used to study fibroma. Human ortholog(s) of this gene implicated in cerebellofaciodental syndrome. Orthologous to human BRF1 (BRF1 RNA polymerase III transcription initiation factor subunit). [provided by Alliance of Genome Resources, Apr 2022]

Brf1 基因产物(1)

mRNA Protein Name
NM_001399505.1 NP_001386434.1 transcription factor IIIB 90 kDa subunit
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of transcription by RNA polymerase III IMP
IMP: 通过突变表型推断
18456653 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor IIIB 90 kDa subunit

BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB

BRF1, RNA polymerase III transcription initiation factor 90 subunit

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01616 BRF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16041 ZFP36L1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18914 Brf1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21270 Zfp36l1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25405 Brf1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Brf1 NCBI NCBI:2972
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