2. Gene
  3. Shmt2 - serine hydroxymethyltransferase 2 Gene

Shmt2 - serine hydroxymethyltransferase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 299857 | 基因类型: protein coding

关于 Shmt2

功能概要

Enables several functions, including L-allo-threonine aldolase activity; glycine hydroxymethyltransferase activity; and pyridoxal phosphate binding activity. Involved in L-serine biosynthetic process; glycine biosynthetic process from serine; and positive regulation of cell population proliferation. Located in mitochondrial inner membrane; mitochondrial intermembrane space; and mitochondrial matrix. Orthologous to human SHMT2 (serine hydroxymethyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Shmt2 基因产物(3)

mRNA Protein Name
NM_001008322.2 NP_001008323.1 serine hydroxymethyltransferase, mitochondrial isoform 1
NM_001393833.1 NP_001380762.1 serine hydroxymethyltransferase, mitochondrial isoform 2
NM_001393834.1 NP_001380763.1 serine hydroxymethyltransferase, mitochondrial isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables L-allo-threonine aldolase activity IDA
IDA: 通过直接分析推断
3110140 RGD
enables amino acid binding IPI
IPI: 通过物理相互作用推断
3110140 RGD
enables glycine hydroxymethyltransferase activity IDA
IDA: 通过直接分析推断
3110140 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
3110140 RGD
enables pyridoxal phosphate binding IDA
IDA: 通过直接分析推断
3110140 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in L-serine biosynthetic process IDA
IDA: 通过直接分析推断
10457370 RGD
involved in glycine biosynthetic process IDA
IDA: 通过直接分析推断
3110140 RGD
involved in glycine biosynthetic process from serine IDA
IDA: 通过直接分析推断
3110140 RGD
involved in glycine metabolic process IDA
IDA: 通过直接分析推断
10457370 RGD
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
12138190 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
4107181 RGD
located in mitochondrial matrix IDA
IDA: 通过直接分析推断
4107181 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

serine hydroxymethyltransferase, mitochondrial

serine hydroxymethyltransferase 2 (mitochondrial)

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-129226 SHMT-IN-2 Inhibitor 99.60% 否
HY-134978 (Rac)-SHIN2 Inhibitor 99.09% 否
HY-148545 SHMT-IN-3 Inhibitor ≥98.0% 否
HY-RS12877 SHMT2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17061 Shmt2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23505 Shmt2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Shmt2 NCBI NCBI:6472
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