2. Gene
  3. Ercc2 - ERCC excision repair 2, TFIIH core complex helicase subunit Gene

Ercc2 - ERCC excision repair 2, TFIIH core complex helicase subunit Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 308415 | 基因类型: protein coding

关于 Ercc2

功能概要

Predicted to enable several functions, including 5'-3' DNA helicase activity; protein C-terminus binding activity; and protein N-terminus binding activity. Involved in embryonic organ development and response to hypoxia. Part of transcription factor TFIIH core complex. Biomarker of asphyxia neonatorum. Human ortholog(s) of this gene implicated in several diseases, including acoustic neuroma; acquired immunodeficiency syndrome; carcinoma (multiple); hematologic Cancer (multiple); and xeroderma pigmentosum (multiple). Orthologous to human ERCC2 (ERCC excision repair 2, TFIIH core complex helicase subunit). [provided by Alliance of Genome Resources, Apr 2022]

Ercc2 基因产物(2)

mRNA Protein Name
NM_001172809.1 NP_001166280.1 general transcription and DNA repair factor IIH helicase subunit XPD
NM_001172809.1 NP_001166280.1 general transcription and DNA repair factor IIH helicase subunit XPD
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in embryonic organ development IEP
IEP: 通过表达模式推断
11425516 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
9763211 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of transcription factor TFIIH core complex IDA
IDA: 通过直接分析推断
8855220 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

general transcription and DNA repair factor IIH helicase subunit XPD

TFIIH basal transcription factor complex helicase XPD subunit

excision repair cross-complementation group 2

excision repair cross-complementing rodent repair deficiency, complementation group 2

rCG54110-like

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04479 ERCC2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22491 Ercc2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29014 Ercc2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ercc2 NCBI NCBI:2068
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