1. Gene
  2. Herc2 - HECT and RLD domain containing E3 ubiquitin protein ligase 2 Gene

Herc2 - HECT and RLD domain containing E3 ubiquitin protein ligase 2 Gene

种属: Rattus norvegicus

基因 ID: 308669 | 基因类型: protein coding

关于 Herc2

功能概要

Predicted to enable SUMO binding activity; ubiquitin protein Ligase activity; and ubiquitin protein Ligase binding activity. Predicted to be involved in cellular response to DNA damage stimulus; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to act upstream of or within spermatogenesis. Predicted to be located in cytosol; nucleus; and plasma membrane. Predicted to be active in cytoplasm and membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability and pigmentation disease. Orthologous to human HERC2 (HECT and RLD domain containing E3 ubiquitin protein Ligase 2). [provided by Alliance of Genome Resources, Apr 2022]

Herc2 基因产物(1)

mRNA Protein Name
NM_001107520.1 NP_001100990.1 E3 ubiquitin-protein ligase HERC2
蛋白主名 其他名称

E3 ubiquitin-protein ligase HERC2

hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 2

hect domain and RLD 2

probable E3 ubiquitin-protein ligase HERC2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Herc2 NCBI NCBI:8924