2. Gene
  3. Ncoa1 - nuclear receptor coactivator 1 Gene

Ncoa1 - nuclear receptor coactivator 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: SRC-1

基因 ID: 313929 | 基因类型: protein coding

关于 Ncoa1

功能概要

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and nuclear receptor binding activity. Involved in several processes, including animal organ development; estrous cycle; and mating behavior. Located in cytoplasm; neuron projection; and nucleus. Biomarker of hypothyroidism. Orthologous to human NCOA1 (nuclear receptor coactivator 1). [provided by Alliance of Genome Resources, Apr 2022]

Ncoa1 基因产物(1)

mRNA Protein Name
NM_001395569.1 NP_001382498.1 nuclear receptor coactivator 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15166231 RGD
enables nuclear estrogen receptor binding IPI
IPI: 通过物理相互作用推断
19460436 RGD
enables nuclear receptor binding IPI
IPI: 通过物理相互作用推断
18566116 RGD
enables nuclear retinoic acid receptor binding IPI
IPI: 通过物理相互作用推断
15234273 RGD
enables nuclear retinoid X receptor binding IPI
IPI: 通过物理相互作用推断
15234273 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
15234273 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hormone stimulus IMP
IMP: 通过突变表型推断
9808623 RGD
involved in cerebellum development IEP
IEP: 通过表达模式推断
10803578 RGD
involved in cerebral cortex development IEP
IEP: 通过表达模式推断
12551846 RGD
involved in estrous cycle IEP
IEP: 通过表达模式推断
15862975 RGD
involved in hippocampus development IEP
IEP: 通过表达模式推断
22085911 RGD
involved in hypothalamus development IEP
IEP: 通过表达模式推断
12551846 RGD
involved in lactation IEP
IEP: 通过表达模式推断
15946693 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
16189181 RGD
involved in male mating behavior IMP
IMP: 通过突变表型推断
10861018 RGD
involved in positive regulation of female receptivity IMP
IMP: 通过突变表型推断
16769066 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
17481888 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
9564863 RGD
involved in response to estradiol IMP
IMP: 通过突变表型推断
9808623 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
9564863 RGD
involved in response to progesterone IMP
IMP: 通过突变表型推断
9808623 RGD
involved in response to retinoic acid IMP
IMP: 通过突变表型推断
9808623 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear receptor coactivator 1

steroid receptor coactivator 1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-146288 LXR agonist 2 Agonist / 否
HY-RS09089 NCOA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22672 Ncoa1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29186 Ncoa1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ncoa1 NCBI NCBI:8648
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