2. Gene
  3. EHMT1 - euchromatic histone lysine methyltransferase 1 Gene

EHMT1 - euchromatic histone lysine methyltransferase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：常染色质组蛋白赖氨酸甲基转移酶 1

种属: Rattus norvegicus

基因 ID: 362078 | 基因类型: protein coding

关于 EHMT1

Primary_assembly 3: 7,580,683-7,729,007 reverse strand.mRatBN7.2:CM026976.1

This gene has 5 transcripts (splice variants), 314 orthologues, 23 paralogues and is associated with 16 phenotypes. Biased expression in Thymus (RPKM 14.5), Adrenal (RPKM 113.7) and 9 other tissues.

功能概要

预计该基因编码的蛋白可启动多种功能，包括 C2H2 锌指结构域结合活性；组蛋白-赖氨酸 N-甲基转移酶活性；和 p53 结合活性。参与对杀菌剂的反应。预计位于核体。该基因的人类直系同源物与 Kleefstra 综合征和 Kleefstra 综合征 1 相关。与人类 EHMT1（常染色质组蛋白赖氨酸甲基转移酶 1）直系同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable several functions, including C2H2 zinc finger domain binding activity; histone-lysine N-methyltransferase activity; and p53 binding activity. Involved in response to fungicide. Predicted to be located in nuclear body. Human ortholog(s) of this gene implicated in Kleefstra syndrome and Kleefstra syndrome 1. Orthologous to human EHMT1 (euchromatic histone lysine methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

EHMT1 基因产物(1)

mRNA Protein Name
NM_001108572.1 NP_001102042.1 histone-lysine N-methyltransferase EHMT1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to fungicide IEP
IEP: 通过表达模式推断
22496781 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

EHMT1 蛋白结构

EHMT_ZBD

EHMT_ZBD: cd20905 (527 - 657)

Ank_2

Ank_2: pfam12796 (753 - 847)

ANK

ANK: sd00045 (785 - 814)

ANK

ANK: sd00045 (816 - 847)

Ank_2

Ank_2: pfam12796 (821 - 914)

ANK

ANK: sd00045 (849 - 881)

ANK

ANK: sd00045 (883 - 914)

Ank_2

Ank_2: pfam12796 (888 - 980)

ANK

ANK: sd00045 (916 - 947)

ANK

ANK: sd00045 (949 - 980)

SET_EHMT1

SET_EHMT1: cd10535 (1047 - 1277)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1310 a.a.
蛋白主名 其他名称

histone-lysine N-methyltransferase EHMT1

euchromatic histone methyltransferase 1

euchromatic histone-lysine N-methyltransferase 1

histone-lysine N-methyltransferase EHMT1-like

histone-lysine N-methyltransferase, H3 lysine-9 specific 5

相关产品

Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15273 UNC0638 99.48% 否
HY-12583 A-366 Inhibitor 98.01% 否
HY-13808 UNC 0631 Inhibitor 99.27% 否
HY-13807 UNC0646 Inhibitor 99.38% 否
HY-111778 EHMT2-IN-1 Inhibitor 99.85% 否
HY-111904 EHMT2-IN-2 Inhibitor ≥99.0% 否
HY-148817 WDR5-0102 Inhibitor 97.07% 否
HY-RS04227 EHMT1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS04228 Ehmt1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS04229 EHMT1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-110093 UNC0638 hydrate Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens EHMT1 NCBI NCBI:79813
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