2. Gene
  3. Rrm2 - ribonucleotide reductase regulatory subunit M2 Gene

Rrm2 - ribonucleotide reductase regulatory subunit M2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 362720 | 基因类型: protein coding

关于 Rrm2

功能概要

Predicted to enable ferric iron binding activity; protein homodimerization activity; and ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Involved in mitotic cell cycle; positive regulation of cell population proliferation; and pyrimidine nucleobase metabolic process. Located in nuclear envelope. Used to study endometrial adenocarcinoma. Biomarker of urinary bladder Cancer. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human RRM2 (ribonucleotide reductase regulatory subunit M2). [provided by Alliance of Genome Resources, Apr 2022]

Rrm2 基因产物(1)

mRNA Protein Name
NM_001025740.2 NP_001020911.1 ribonucleoside-diphosphate reductase subunit M2
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
17404105 RGD
involved in pyrimidine nucleobase metabolic process IEP
IEP: 通过表达模式推断
10204803 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nuclear envelope IDA
IDA: 通过直接分析推断
2205248 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ribonucleoside-diphosphate reductase subunit M2

Ribonucleotide reductase 2

ribonucleotide reductase M2 polypeptide

ribonucleotide reductase small chain

ribonucleotide reductase small subunit

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-30272 Monobenzone 99.93% 否
HY-B2116 Osalmid Inhibitor 99.80% 否
Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-153898 rTRD01 Ligand 99.10% 否
HY-112358 GW8510 Inhibitor 99.04% 否
HY-153736 NSC 194308 98.40% 否
HY-RS12286 RRM2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12287 RRM2B Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS16616 Rrm2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS21746 Rrm2b Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS23051 Rrm2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS28263 Rrm2b Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rrm2 NCBI NCBI:6241
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