2. Gene
  3. Crtc1 - CREB regulated transcription coactivator 1 Gene

Crtc1 - CREB regulated transcription coactivator 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mect1; TORC1; TORC-1; mKIAA0616

基因 ID: 382056 | 基因类型: protein coding

关于 Crtc1

功能概要

Predicted to enable cAMP response element binding protein binding activity. Involved in entrainment of circadian clock by photoperiod and positive regulation of CREB transcription factor activity. Acts upstream of or within several processes, including energy homeostasis; memory; and negative regulation of membrane hyperpolarization. Located in cytoplasm and nucleus. Is expressed in limb and limb mesenchyme. Used to study major depressive disorder. Orthologous to human CRTC1 (CREB regulated transcription coactivator 1). [provided by Alliance of Genome Resources, Apr 2022]

Crtc1 基因产物(17)

mRNA Protein Name
NM_001004062.3 NP_001004062.1 CREB-regulated transcription coactivator 1 isoform 2
NM_001404415.1 NP_001391344.1 CREB-regulated transcription coactivator 1 isoform 1
NM_001404416.1 NP_001391345.1 CREB-regulated transcription coactivator 1 isoform 3
NM_001404417.1 NP_001391346.1 CREB-regulated transcription coactivator 1 isoform 4
NM_001404418.1 NP_001391347.1 CREB-regulated transcription coactivator 1 isoform 5
NM_001404419.1 NP_001391348.1 CREB-regulated transcription coactivator 1 isoform 6
NM_001404420.1 NP_001391349.1 CREB-regulated transcription coactivator 1 isoform 7
NM_001404421.1 NP_001391350.1 CREB-regulated transcription coactivator 1 isoform 8
NM_001404422.1 NP_001391351.1 CREB-regulated transcription coactivator 1 isoform 9
NM_001404423.1 NP_001391352.1 CREB-regulated transcription coactivator 1 isoform 10
NM_001404424.1 NP_001391353.1 CREB-regulated transcription coactivator 1 isoform 11
NM_001404425.1 NP_001391354.1 CREB-regulated transcription coactivator 1 isoform 12
NM_001404426.1 NP_001391355.1 CREB-regulated transcription coactivator 1 isoform 13
NM_001404427.1 NP_001391356.1 CREB-regulated transcription coactivator 1 isoform 14
NM_001404428.1 NP_001391357.1 CREB-regulated transcription coactivator 1 isoform 15
NM_001404429.1 NP_001391358.1 CREB-regulated transcription coactivator 1 isoform 16
NM_001404430.1 NP_001391359.1 CREB-regulated transcription coactivator 1 isoform 16
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
30611118 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within energy homeostasis IMP
IMP: 通过突变表型推断
19734865 MGI
involved in entrainment of circadian clock by photoperiod IMP
IMP: 通过突变表型推断
23993098 MGI
acts upstream of or within memory IMP
IMP: 通过突变表型推断
23223304 MGI
acts upstream of or within metabolic process IMP
IMP: 通过突变表型推断
19734865 MGI
acts upstream of or within negative regulation of membrane hyperpolarization IDA
IDA: 通过直接分析推断
23223304 MGI
involved in positive regulation of CREB transcription factor activity IMP
IMP: 通过突变表型推断
23993098 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
23223304 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
23223304 MGI
located in nucleus IDA
IDA: 通过直接分析推断
23223304 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CREB-regulated transcription coactivator 1

mucoepidermoid carcinoma translocated 1

mucoepidermoid carcinoma translocated protein 1 homolog

transducer of CREB protein 1

transducer of regulated cAMP response element-binding protein 1

相关产品

Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N0059 D-Arabinose ≥99.0% 否
HY-N7082 D-Arabinopyranose 99.94% 否
HY-N0059R D-Arabinose (Standard) / 否
HY-N0059S D-Arabinose-13C / 否
HY-N0059S1 D-Arabinose-13C-1 / 否
HY-N0059S2 D-arabinose-13C-2 / 否
HY-N0059S3 D-Arabinose-13C-3 / 否
HY-N0059S4 D-Arabinose-d2 / 否
HY-N0059S5 D-Arabinose-d5 / 否
HY-N0059S6 D-Arabinose-d6 / 否
HY-N7082S D-Arabinopyranose-13C5 / 否
HY-RS03200 CRTC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22459 Crtc1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Crtc1 NCBI NCBI:23373
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