2. Gene
  3. MEX3D - mex-3 RNA binding family member D Gene

MEX3D - mex-3 RNA binding family member D Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：mex-3 RNA 结合家族成员 D

种属: Homo sapiens

同用名: MEX3; TINO; RKHD1; MEX-3D; RNF193; OK/SW-cl.4

基因 ID: 399664 | 基因类型: protein coding

关于 MEX3D

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,554,672-1,568,325 (from NCBI)

This gene has 2 transcripts (splice variants), 167 orthologues and 3 paralogues. Broad expression in testis (RPKM 6.0), fat (RPKM 4.9) and 24 other tissues.

功能概要

启用 mRNA 3'-UTR AU 富集区结合活性。位于细胞质的细胞核和核周区。 [由基因组资源联盟提供，2022 年 4 月]

Enables mRNA 3'-UTR AU-rich region binding activity. Located in nucleus and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MEX3D 基因产物(2)

mRNA Protein Name
NM_001174118.2 NP_001167589.1 RNA-binding protein MEX3D isoform 2
NM_203304.4 NP_976049.3 RNA-binding protein MEX3D isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA 3'-UTR AU-rich region binding IDA
IDA: 通过直接分析推断
14769789 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
14769789 GOA
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
14769789 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MEX3D 蛋白结构

KH_1

KH_1: KH domain (181 - 240)

KH_1

KH_1: KH domain (275 - 334)

zf-C3HC4_3

zf-C3HC4_3: Zinc finger, C3HC4 type (RING finger) (598 - 644)

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  • 651 a.a.
蛋白主名 其他名称

RNA-binding protein MEX3D

RING finger and KH domain-containing protein 1

关联疾病

疾病名称 别名
Arthrogryposis, Distal, Type 5

Oculomelic Amyoplasia

Distal Arthrogryposis Type 5

Distal Arthrogryposis Type Iib

DA5

Arthrogryposis With Oculomotor Limitation And Electroretinal Abnormalities

Daiib

Distal Arthrogryposis Type 2b

Arthrogryposis-Oculomotor Limitation-Electroretinal Anomalies Syndrome

Distal Arthrogryposis With Ophthalmoplegia

Arthrogryposis- Oculomotor Limitation-Electroretinal Anomalies Syndrome

Arthrogryposis, Distal, Type Iib

Da2b

Freeman-Sheldon Syndrome Variant

Sheldon-Hall Syndrome

Arthogryposis With Oculomotor Limitation And Electroretinal Abnormalities

Arthrogryposis Ophthalmoplegia Retinopathy

Arthrogryposis, Distal, 5

Arthrogryposis, Distal, Type 2b
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08375 MEX3D Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21644 Mex3d Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28162 Mex3d Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus MEX3D RGD RGD:1310576
Mus musculus MEX3D MGD MGI:2681847
Bos taurus MEX3D VGNC VGNC:106821
Canis familiaris MEX3D VGNC VGNC:81279
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