2. Gene
  3. Olig2 - oligodendrocyte transcription factor 2 Gene

Olig2 - oligodendrocyte transcription factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: RK17; Olg-2; Bhlhb1; Oligo2; bHLHe19

基因 ID: 50913 | 基因类型: protein coding

关于 Olig2

功能概要

Enables DNA-binding transcription factor activity, RNA polymerase II-specific; HMG box domain binding activity; and identical protein binding activity. Acts upstream of or within negative regulation of neuron differentiation; negative regulation of transcription by RNA polymerase II; and nervous system development. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; epidermis; future brain; genitourinary system; and retina. Orthologous to human OLIG2 (oligodendrocyte transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Olig2 基因产物(1)

mRNA Protein Name
NM_016967.2 NP_058663.2 oligodendrocyte transcription factor 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
14573534 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
15655114 MGI
enables HMG box domain binding IPI
IPI: 通过物理相互作用推断
16582099 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
15655114 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
14573534 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within myelination IMP
IMP: 通过突变表型推断
16436615 MGI
acts upstream of or within negative regulation of neuron differentiation IDA
IDA: 通过直接分析推断
11566099 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15655114 MGI
acts upstream of or within nervous system development IDA
IDA: 通过直接分析推断
14573534 MGI
acts upstream of neuron differentiation IDA
IDA: 通过直接分析推断
11566099 MGI
acts upstream of or within neuron fate commitment IMP
IMP: 通过突变表型推断
11955448 MGI
acts upstream of oligodendrocyte differentiation IGI
IGI: 通过遗传相互作用推断
11566099 MGI
acts upstream of or within oligodendrocyte differentiation IMP
IMP: 通过突变表型推断
16436615 MGI
acts upstream of or within positive regulation of oligodendrocyte differentiation IGI
IGI: 通过遗传相互作用推断
11566099 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
14573534 MGI
acts upstream of or within spinal cord motor neuron differentiation IMP
IMP: 通过突变表型推断
21338882 MGI
acts upstream of or within spinal cord oligodendrocyte cell differentiation IGI
IGI: 通过遗传相互作用推断
18287202 MGI
acts upstream of or within spinal cord oligodendrocyte cell fate specification IDA
IDA: 通过直接分析推断
18287202 MGI
acts upstream of or within thalamus development IMP
IMP: 通过突变表型推断
19357274 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
14573534 MGI
located in nucleus IDA
IDA: 通过直接分析推断
14573534 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

oligodendrocyte transcription factor 2

Olig2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Olig2 Q9EQW6 Id4 Mus musculus P41139
Anti Bait CoIP
15280210
种属内
Olig2 Q9EQW6 Id4 Mus musculus P41139
Confocal
15280210
种属内
Olig2 Q9EQW6 Id4 Mus musculus P41139
Y2H
15280210
种属内
Olig2 Q9EQW6 Id4 Mus musculus P41139
Anti Tag CoIP
15280210
种属内
Olig2 Q9EQW6 Id2 Mus musculus P41136
Anti Bait CoIP
15280210
种属内
Olig2 Q9EQW6 Id2 Mus musculus P41136
Confocal
15280210
种属内
Olig2 Q9EQW6 Id2 Mus musculus P41136
Y2H
15280210
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-125427 SKOG102 Inhibitor 99.09% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Olig2 NCBI NCBI:10215
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