ASB4 - ankyrin repeat and SOCS box containing 4 Gene

中文名称：含锚蛋白重复和 SOCS 盒 4

种属: Homo sapiens

同用名: ASB-4

关于 ASB4

功能概要

由该基因编码的蛋白质是锚蛋白重复序列和含有 SOCS 盒 (ASB) 的蛋白质家族的成员。它们包含锚蛋白重复序列和 SOCS 框域。 SOCS 盒用于将细胞因子信号转导抑制因子 (SOCS) 蛋白及其结合伙伴与 elongin B 和 C 复合物偶联，可能靶向它们进行降解。已经描述了该基因的多个可变剪接转录物变体，但一些全长序列尚不清楚。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known. [provided by RefSeq, Jul 2008]