2. Gene
  3. PRKG1 - Prkg1 protein kinase cGMP-dependent 1 Gene

PRKG1 - Prkg1 protein kinase cGMP-dependent 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Pkgi; cGk1

基因 ID: 54286 | 基因类型: protein coding

关于 PRKG1

功能概要

Enables identical protein binding activity and mitogen-activated protein kinase p38 binding activity. Involved in several processes, including cell growth involved in cardiac muscle cell development; regulation of cellular biosynthetic process; and regulation of ion transport. Located in several cellular components, including Golgi apparatus; acrosomal vesicle; and nucleoplasm. Colocalizes with sarcolemma. Biomarker of allergic rhinitis; hypertension; hypogonadism; impotence; and obesity. Human ortholog(s) of this gene implicated in thoracic aortic aneurysm. Orthologous to human PRKG1 (protein kinase cGMP-dependent 1). [provided by Alliance of Genome Resources, Apr 2022]

PRKG1 基因产物(1)

mRNA Protein Name
NM_001105731.4 NP_001099201.3 cGMP-dependent protein kinase 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
23454089 RGD
enables mitogen-activated protein kinase p38 binding IDA
IDA: 通过直接分析推断
16943189 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell growth involved in cardiac muscle cell development IMP
IMP: 通过突变表型推断
19542178 RGD
involved in cerebellum development IEP
IEP: 通过表达模式推断
15763176 RGD
involved in heart development IEP
IEP: 通过表达模式推断
2792381 RGD
involved in negative regulation of glutamate secretion IMP
IMP: 通过突变表型推断
10081919 RGD
involved in negative regulation of inositol phosphate biosynthetic process IMP
IMP: 通过突变表型推断
7535379 RGD
involved in negative regulation of smooth muscle cell migration IMP
IMP: 通过突变表型推断
15576431 RGD
involved in positive regulation of circadian rhythm IMP
IMP: 通过突变表型推断
12930792 RGD
involved in positive regulation of cytosolic calcium ion concentration IMP
IMP: 通过突变表型推断
8706897 RGD
involved in positive regulation of large conductance calcium-activated potassium channel activity IMP
IMP: 通过突变表型推断
23407708 RGD
involved in regulation of testosterone biosynthetic process IMP
IMP: 通过突变表型推断
22429315 RGD
involved in spermatid development IEP
IEP: 通过表达模式推断
15713832 RGD
involved in vasodilation IMP
IMP: 通过突变表型推断
8719784 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in acrosomal vesicle IDA
IDA: 通过直接分析推断
15713832 RGD
located in nucleoplasm IDA
IDA: 通过直接分析推断
18474265 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
12855709 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cGMP-dependent protein kinase 1

cAMP-dependent protein kinase catalytic subunit PRKX-like

cGMP dependent protein kinase type 1

protein kinase, cGMP-dependent, type 1

protein kinase, cGMP-dependent, type I

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11154 PRKG1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20087 Prkg1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26590 Prkg1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens PRKG1 NCBI NCBI:5592
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