PPM1G - protein phosphatase, Mg2+/Mn2+ dependent 1G Gene

中文名称：蛋白磷酸酶，Mg2+/Mn2+ 依赖性 1G

种属: Homo sapiens

同用名: PP2CG; PPP2CG; PP2CGAMMA

关于 PPM1G

功能概要

该基因编码的蛋白质是 Ser/Thr 蛋白磷酸酶 PP2C 家族的成员。已知 PP2C 家族成员是细胞应激反应途径的负调节剂。发现这种磷酸酶负责 Pre-mRNA 剪接因子的去磷酸化，这对于功能性剪接体的形成很重要。对小鼠中相似基因的研究表明，这种磷酸酶在调节细胞周期进程中发挥作用。[RefSeq 提供，2010 年 4 月]

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This Phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this Phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010]