2. Gene
  3. DEPDC1 - DEP domain containing 1 Gene

DEPDC1 - DEP domain containing 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 DEP 域 1

种属: Homo sapiens

同用名: DEP.8; SDP35; DEPDC1A; DEPDC1-V2

基因 ID: 55635 | 基因类型: protein coding

关于 DEPDC1

Cytogenetic location: 1p31.3 Genomic coordinates (GRCh38): 1:68,474,152-68,497,082 (from NCBI)

This gene has 5 transcripts (splice variants), 207 orthologues and 3 paralogues. Biased expression in testis (RPKM 5.4), lymph node (RPKM 3.0) and 13 other tissues.

功能概要

预测启用 GTPase 激活剂活动。参与转录的负调控，以 DNA 为模板。位于核内。转录抑制复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable GTPase activator activity. Involved in negative regulation of transcription, DNA-templated. Located in nucleus. Part of transcription repressor complex. [provided by Alliance of Genome Resources, Apr 2022]

DEPDC1 基因产物(2)

mRNA Protein Name
NM_001114120.3 NP_001107592.1 DEP domain-containing protein 1A isoform a
NM_017779.6 NP_060249.2 DEP domain-containing protein 1A isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20587513 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
20587513 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
20587513 GOA
part of transcription repressor complex IDA
IDA: 通过直接分析推断
20587513 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DEPDC1 蛋白结构

DEP

DEP: Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) (27 - 106)

  • 0
  • 200
  • 400
  • 600
  • 811 a.a.
蛋白主名 其他名称

DEP domain-containing protein 1A

cell cycle control protein SDP35

关联疾病

疾病名称 别名
Bladder Cancer

Urinary Bladder Cancer

Bladder Carcinoma

Urinary Bladder Carcinoma

Bladder Neoplasm

Bladder Tumor

Cancer, Bladder

Malignant Neoplasm Of Urinary Bladder

Carcinoma Of Bladder

Bladder Cancer, Somatic

Tumor Of The Bladder

Carcinoma Of Urinary Bladder

Bladder Carcinoma Urinary

Cancer Of The Urinary Bladder

Cancer, Urinary Bladder

Malignant Bladder Neoplasm

Malignant Bladder Tumor

Neoplasm Of The Bladder

Neoplasm Of The Urinary Bladder

Tumor Of The Urinary Bladder

Urinary Bladder Neoplasm

BLC

Urothelial Carcinoma Of The Bladder

Bladder Tumors

Urinary Bladder Neoplasms

Bladder Cancer Nos

Vesical Cancer Nos

Malignant Neoplasm Of Bladder, Part Unspecified

Malignant Tumour Of Urinary Bladder

Primary Malignant Neoplasm Of Bladder
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03693 DEPDC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS03694 DEPDC1B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27053 Depdc1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris DEPDC1 VGNC VGNC:39896
Rattus norvegicus DEPDC1 RGD RGD:1306987
Bos taurus DEPDC1 VGNC VGNC:55165
Mus musculus DEPDC1 MGD MGI:1923381
Macaca mulatta DEPDC1 VGNC VGNC:99886
Felis catus DEPDC1 VGNC VGNC:61443
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