2. Gene
  3. KCMF1 - potassium channel modulatory factor 1 Gene

KCMF1 - potassium channel modulatory factor 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：钾通道调节因子 1

种属: Homo sapiens

同用名: FIGC; PCMF; ZZZ1; DEBT91

基因 ID: 56888 | 基因类型: protein coding

关于 KCMF1

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:84,971,161-85,059,472 (from NCBI)

This gene has 4 transcripts (splice variants) and 231 orthologues. Ubiquitous expression in testis (RPKM 9.7), thyroid (RPKM 7.1) and 25 other tissues.

功能概要

启用泛素蛋白连接酶活性。预计参与突触信号。位于胞质溶胶中。 [由基因组资源联盟提供，2022 年 4 月]

Enables ubiquitin protein Ligase activity. Predicted to be involved in synaptic signaling. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

KCMF1 基因产物(1)

mRNA Protein Name
NM_020122.5 NP_064507.3 E3 ubiquitin-protein ligase KCMF1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ubiquitin protein ligase activity IDA
IDA: 通过直接分析推断
15581609 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of HRI-mediated signaling IDA
IDA: 通过直接分析推断
38297121 GOA
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
37891180 GOA
involved in protein K48-linked ubiquitination IDA
IDA: 通过直接分析推断
38297121 GOA
involved in protein K63-linked ubiquitination IDA
IDA: 通过直接分析推断
34893540 GOA
involved in response to oxidative stress IDA
IDA: 通过直接分析推断
34893540 GOA
involved in ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
34893540 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytoplasm IDA
IDA: 通过直接分析推断
38297121 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

KCMF1 蛋白结构

ZZ

ZZ: Zinc finger, ZZ type (4 - 47)

zf-Di19

zf-Di19: Drought induced 19 protein (Di19), zinc-binding (76 - 137)

  • 0
  • 100
  • 200
  • 300
  • 381 a.a.
蛋白主名 其他名称

E3 ubiquitin-protein ligase KCMF1

FGF-induced in gastric cancer

关联疾病

疾病名称 别名
Epidermodysplasia Verruciformis 1

Epidermodysplasia Verruciformis

Epidermodysplasia Verruciformis, Susceptibility To, 1

Lutz-Lewandowsky Epidermodysplasia Verruciformis

EV1

Lewandowsky-Lutz Syndrome

Ev
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07096 KCMF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21607 Kcmf1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28125 Kcmf1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus KCMF1 RGD RGD:1591490
Mus musculus KCMF1 MGD MGI:1921537
Bos taurus KCMF1 VGNC VGNC:30419
Macaca mulatta KCMF1 VGNC VGNC:73868
Canis familiaris KCMF1 VGNC VGNC:58310
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