2. Gene
  3. ADCK1 - aarF domain containing kinase 1 Gene

ADCK1 - aarF domain containing kinase 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 aarF 结构域的激酶 1

种属: Homo sapiens

基因 ID: 57143 | 基因类型: protein coding

关于 ADCK1

This gene has 8 transcripts (splice variants), 200 orthologues and 4 paralogues. Ubiquitous expression in brain (RPKM 2.2), thyroid (RPKM 1.9) and 25 other tissues.

功能概要

预计会启用 ATP 结合活性和蛋白丝氨酸/苏氨酸激酶活性。参与线粒体融合的负调节和嵴形成的正调节。预测位于细胞外区域。预计在线粒体内膜中有活性。预计是线粒体膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Involved in negative regulation of mitochondrial fusion and positive regulation of cristae formation. Predicted to be located in extracellular region. Predicted to be active in mitochondrial inner membrane. Predicted to be integral component of mitochondrial membrane. [provided by Alliance of Genome Resources, Apr 2022]

ADCK1 基因产物(8)

mRNA Protein Name
NM_001142545.2 NP_001136017.1 aarF domain-containing protein kinase 1 isoform b
NM_001366485.2 NP_001353414.1 aarF domain-containing protein kinase 1 isoform c
NM_001366486.2 NP_001353415.1 aarF domain-containing protein kinase 1 isoform d
NM_001366487.2 NP_001353416.1 aarF domain-containing protein kinase 1 isoform e
NM_001366488.2 NP_001353417.1 aarF domain-containing protein kinase 1 isoform f
NM_001366489.2 NP_001353418.1 aarF domain-containing protein kinase 1 isoform g
NM_001366490.2 NP_001353419.1 aarF domain-containing protein kinase 1 isoform h
NM_020421.4 NP_065154.2 aarF domain-containing protein kinase 1 isoform a precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of mitochondrial fusion IMP
IMP: 通过突变表型推断
31125351 GOA
involved in positive regulation of cristae formation IMP
IMP: 通过突变表型推断
31125351 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
33988507 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ADCK1 蛋白结构

ABC1

ABC1: ABC1 family (136 - 252)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 523 a.a.
蛋白主名 其他名称

aarF domain-containing protein kinase 1

关联疾病

疾病名称 别名
Water-Clear Cell Adenoma
Coenzyme Q10 Deficiency, Primary, 4

Scar9

Spinocerebellar Ataxia, Autosomal Recessive 9

Autosomal Recessive Ataxia Due To Ubiquinone Deficiency

COQ10D4

Arca2

Autosomal Recessive Cerebellar Ataxia Type 2

Primary Coenzyme Q10 Deficiency 4

Autosomal Recessive Ataxia Due To Coenzyme Q10 Deficiency

Autosomal Recessive Spinocerebellar Ataxia Type 9

Autosomal Recessive Spinocerebellar Ataxia 9

Spinocerebellar Ataxia Autosomal Recessive 9

Coenzyme Q10 Deficiency, Primary, Type 4

Ataxia, Spinocerebellar, Autosomal Recessive, Type 9
Lipoadenoma
Parathyroid Carcinoma

Parathyroid Cancer

Parathyroid Neoplasms

Malignant Tumor Of Parathyroid Gland

PRTC

Carcinoma Of Parathyroid Gland

Malignant Neoplasm Of Parathyroid Gland

Parathyroid Gland Adenocarcinoma

Parathyroid Gland Cancer

Parathyroid Neoplasm

Parathyroid Gland Carcinoma

Malignant Neoplasm Of The Parathyroid

Neoplasm Of Parathyroid Gland

Parathyroid Gland Neoplasm

Cancer Of The Parathyroid

Cancer Of The Parathyroid Gland

Malignant Neoplasm Of Parathyroid

Malignant Parathyroid Gland Neoplasm

Malignant Parathyroid Gland Tumor

Malignant Parathyroid Neoplasm

Malignant Parathyroid Tumor

Malignant Tumor Of Parathyroid

Parathyroid Adenocarcinoma

Neoplasm Of The Parathyroid Gland

Carcinoma, Parathyroid
Coenzyme Q10 Deficiency Disease

Coenzyme Q10 Deficiency

Coq10 Deficiency

Primary Coenzyme Q10 Deficiency

Coenzyme Q Deficiency

Coq Deficiency

Primary Coq10 Deficiency

Ubiquinone Deficiency

Coenzyme Q10 Deficiency, Primary

Coq10 Deficiency, Primary
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00323 ADCK1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ADCK1 VGNC VGNC:69472
Bos taurus ADCK1 VGNC VGNC:25639
Rattus norvegicus ADCK1 RGD RGD:1308263
Felis catus ADCK1 VGNC VGNC:59610
Mus musculus ADCK1 MGD MGI:1919363
Canis familiaris ADCK1 VGNC VGNC:37615
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