2. Gene
  3. HES4 - hes family bHLH transcription factor 4 Gene

HES4 - hes family bHLH transcription factor 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品

中文名称：hes 家族 bHLH 转录因子 4

种属: Homo sapiens

同用名: bHLHb42

基因 ID: 57801 | 基因类型: protein coding

关于 HES4

Cytogenetic location: 1p36.33 Genomic coordinates (GRCh38): 1:998,964-1,000,097 (from NCBI)

This gene has 4 transcripts (splice variants), 171 orthologues and 12 paralogues. Broad expression in fat (RPKM 3.0), prostate (RPKM 2.2) and 19 other tissues.

功能概要

预测可实现 DNA 结合转录因子活性、RNA 聚合酶 II 特异性和 RNA 聚合酶 II 顺式调节区序列特异性 DNA 结合活性。预测参与前/后模式规范和 RNA 聚合酶 II 的转录调节。预测是染色质的一部分。预计活跃于核心。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification and regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

HES4 基因产物(3)

mRNA Protein Name
NM_001142467.2 NP_001135939.1 transcription factor HES-4 isoform 1
NM_001410700.1 NP_001397629.1 transcription factor HES-4 isoform 3
NM_021170.4 NP_066993.1 transcription factor HES-4 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32814053 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

HES4 蛋白结构

HLH

HLH: Helix-loop-helix DNA-binding domain (35 - 91)

Hairy_orange

Hairy_orange: Hairy Orange (109 - 149)

  • 0
  • 100
  • 200
  • 221 a.a.
蛋白主名 其他名称

transcription factor HES-4

bHLH factor Hes4

关联疾病

疾病名称 别名
Trichuriasis

Whipworm Infection

Whipworm Disease

Trichocephaliasis

Infection By Trichuris Trichura

Trichuriasis Infection

Trichuris Trichiura Infection

Infection By Trichuris Trichiura

Trichocephalosis

Infection By Trichocephalus Trichiura

Infection By Trichuris

Infection By Trichuris Trichiuria

Trichuriosis

Whipworm

Infection Due To Trichuris Trichiura

Trichocephalus Infestation

Trichuris Infestation

Whipworm Infestation
Chromosome 1p36 Deletion Syndrome

1p36 Deletion Syndrome

Deletion 1p36

Monosomy 1p36

Subtelomeric 1p36 Deletion

Monosomy 1p36 Syndrome

Distal Monosomy 1p36

Del(1)(P36)

Deletion 1pter

Monosomy 1pter
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06137 HES4 Human Pre-designed siRNA Set A Pre-designed Set / 否
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z