1. Gene
  2. Myoz2 - myozenin 2 Gene

Myoz2 - myozenin 2 Gene

种属: Mus musculus

同用名: Fatz-2; Myozl2; 1110012I24Rik

基因 ID: 59006 | 基因类型: protein coding

关于 Myoz2

功能概要

Enables actin binding activity. Involved in several processes, including negative regulation of calcineurin-NFAT signaling cascade; sarcomere organization; and skeletal muscle fiber adaptation. Located in Z disc and actin Cytoskeleton. Is expressed in several structures, including diaphragm; foregut; heart; liver; and skeletal musculature. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy 16. Orthologous to human MYOZ2 (myozenin 2). [provided by Alliance of Genome Resources, Apr 2022]

Myoz2 基因产物(2)

mRNA Protein Name
NM_001355462.1 NP_001342391.1 myozenin-2 isoform 2
NM_021503.2 NP_067478.1 myozenin-2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IPI
IPI: 通过物理相互作用推断
11114196 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of calcineurin-NFAT signaling cascade IDA
IDA: 通过直接分析推断
15543153 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15543153 MGI
involved in sarcomere organization IDA
IDA: 通过直接分析推断
15543153 MGI
involved in skeletal muscle fiber adaptation IDA
IDA: 通过直接分析推断
15543153 MGI
involved in skeletal muscle tissue development IDA
IDA: 通过直接分析推断
15543153 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Z disc IDA
IDA: 通过直接分析推断
15543153 MGI
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
11114196 MGI
located in actin cytoskeleton IPI
IPI: 通过物理相互作用推断
11114196 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

myozenin-2

FATZ-related protein 2

calsarcin-1

myozenin-like 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Myoz2 NCBI NCBI:51778