2. Gene
  3. Ambra1 - autophagy and beclin 1 regulator 1 Gene

Ambra1 - autophagy and beclin 1 regulator 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Nyw1

基因 ID: 59319 | 基因类型: protein coding

关于 Ambra1

功能概要

Predicted to enable GTPase binding activity and ubiquitin protein Ligase binding activity. Involved in cellular response to starvation; negative regulation of cardiac muscle cell apoptotic process; and positive regulation of Autophagy. Predicted to be located in axoneme; cytosol; and phagocytic vesicle. Predicted to be active in intracellular membrane-bounded organelle. Predicted to colocalize with mitochondrion. Orthologous to human AMBRA1 (Autophagy and beclin 1 regulator 1). [provided by Alliance of Genome Resources, Apr 2022]

Ambra1 基因产物(1)

mRNA Protein Name
NM_001134341.3 NP_001127813.3 activating molecule in BECN1-regulated autophagy protein 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25117440 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to starvation IEP
IEP: 通过表达模式推断
25117440 RGD
involved in negative regulation of cardiac muscle cell apoptotic process IMP
IMP: 通过突变表型推断
25117440 RGD
involved in positive regulation of autophagy IMP
IMP: 通过突变表型推断
25117440 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
23894530 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

activating molecule in BECN1-regulated autophagy protein 1

autophagy/beclin 1 regulator 1

ischemia related factor NYW-1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00643 AMBRA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21820 Ambra1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28337 Ambra1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ambra1 NCBI NCBI:55626
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