2. Gene
  3. Nmu - neuromedin U Gene

Nmu - neuromedin U Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 63887 | 基因类型: protein coding

关于 Nmu

功能概要

Enables type 1 neuromedin U receptor binding activity and type 2 neuromedin U receptor binding activity. Involved in several processes, including energy homeostasis; negative regulation of digestive system process; and positive regulation of cell communication. Acts upstream of or within neuropeptide signaling pathway. Located in terminal bouton. Used to study obesity. Human ortholog(s) of this gene implicated in obesity. Orthologous to human NMU (neuromedin U). [provided by Alliance of Genome Resources, Apr 2022]

Nmu 基因产物(1)

mRNA Protein Name
NM_022239.3 NP_071575.1 neuromedin-U precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables neuromedin U receptor binding IDA
IDA: 通过直接分析推断
15635449 RGD
enables type 1 neuromedin U receptor binding IDA
IDA: 通过直接分析推断
28874765 RGD
enables type 2 neuromedin U receptor binding IDA
IDA: 通过直接分析推断
28874765 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in eating behavior IDA
IDA: 通过直接分析推断
10894543 RGD
involved in energy homeostasis IDA
IDA: 通过直接分析推断
10894543 RGD
involved in gastric acid secretion IMP
IMP: 通过突变表型推断
12584108 RGD
involved in negative regulation of eating behavior IDA
IDA: 通过直接分析推断
10894543 RGD
involved in negative regulation of feeding behavior IDA
IDA: 通过直接分析推断
20233222 RGD
involved in negative regulation of gastric acid secretion IDA
IDA: 通过直接分析推断
12584108 RGD
involved in negative regulation of gastric emptying IDA
IDA: 通过直接分析推断
12584108 RGD
acts upstream of or within neuropeptide signaling pathway IDA
IDA: 通过直接分析推断
15635449 RGD
involved in photoperiodism IEP
IEP: 通过表达模式推断
17726140 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
28874765 RGD
involved in positive regulation of heart rate IDA
IDA: 通过直接分析推断
11853869 RGD
involved in positive regulation of heat generation IDA
IDA: 通过直接分析推断
11027662 RGD
involved in positive regulation of hormone secretion IMP
IMP: 通过突变表型推断
17726140 RGD
involved in positive regulation of prolactin secretion IDA
IDA: 通过直接分析推断
28874765 RGD
involved in positive regulation of sensory perception of pain IDA
IDA: 通过直接分析推断
12890516 RGD
involved in positive regulation of smooth muscle contraction IDA
IDA: 通过直接分析推断
3178840 RGD
involved in positive regulation of smooth muscle contraction IMP
IMP: 通过突变表型推断
16474416 RGD
involved in positive regulation of stomach fundus smooth muscle contraction IDA
IDA: 通过直接分析推断
2055247 RGD
involved in positive regulation of synaptic transmission IMP
IMP: 通过突变表型推断
15297576 RGD
involved in positive regulation of systemic arterial blood pressure IDA
IDA: 通过直接分析推断
11853869 RGD
involved in regulation of circadian sleep/wake cycle, sleep IDA
IDA: 通过直接分析推断
20233222 RGD
involved in regulation of grooming behavior IDA
IDA: 通过直接分析推断
12399416 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in terminal bouton IDA
IDA: 通过直接分析推断
15297576 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neuromedin-U

neuromedin U precursor-related peptide/neuromedin U preproprotein

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-13513 U-104 Inhibitor 99.95% Phase 2
Pre-clinical Phase
生物活性分子 (15)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12031A U0126 Inhibitor 98.57% 否
HY-12031 U0126-EtOH Inhibitor 99.41% 否
HY-34758 N-Nitroso-N-methylurea ≥98.0% 否
HY-148369 U7D-1 99.68% 否
HY-15997 (-)-U-50488 hydrochloride Inhibitor 99.71% 否
HY-P1238A Neuromedin U, rat TFA 99.69% 否
HY-N6629 3'-Methoxyflavonol 99.92% 否
HY-103496 U-90042 Agonist / 否
HY-P5084 Neuromedin S (human) / 否
HY-RS09391 NMU Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W717139 N-Nitroso-N-methylurea-d5 / 否
HY-123663 U-101958 maleate / 否
HY-RS17526 Nmu Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23983 Nmu Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-P1238 Neuromedin U, rat / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nmu NCBI NCBI:10874
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