2. Gene
  3. Arf1 - ADP-ribosylation factor 1 Gene

Arf1 - ADP-ribosylation factor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 64310 | 基因类型: protein coding

关于 Arf1

功能概要

Enables guanyl ribonucleotide binding activity; magnesium ion binding activity; and Phospholipase D activator activity. Involved in several processes, including Golgi to transport vesicle transport; positive regulation of transport; and postsynapse organization. Located in cytosol and late endosome. Is active in glutamatergic synapse and postsynaptic density. Colocalizes with COPI-coated vesicle; Golgi apparatus; and peroxisomal membrane. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARF1 (ADP ribosylation factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Arf1 基因产物(3)

mRNA Protein Name
NM_001414037.1 NP_001400966.1 ADP-ribosylation factor 1
NM_001414038.1 NP_001400967.1 ADP-ribosylation factor 1
NM_022518.5 NP_071963.1 ADP-ribosylation factor 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GDP binding IDA
IDA: 通过直接分析推断
7552752 RGD
enables GTP binding IDA
IDA: 通过直接分析推断
7552752 RGD
enables magnesium ion binding IDA
IDA: 通过直接分析推断
7552752 RGD
enables phospholipase D activator activity IDA
IDA: 通过直接分析推断
7972129 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
23889934 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Golgi to transport vesicle transport IDA
IDA: 通过直接分析推断
8978816 RGD
involved in actin filament organization IMP
IMP: 通过突变表型推断
23889934 RGD
involved in dendritic spine organization IMP
IMP: 通过突变表型推断
23889934 RGD
involved in long-term synaptic depression IDA
IDA: 通过直接分析推断
23889934 RGD
involved in lysosomal membrane organization IDA
IDA: 通过直接分析推断
9538255 RGD
involved in positive regulation of ER to Golgi vesicle-mediated transport IMP
IMP: 通过突变表型推断
15618550 RGD
involved in positive regulation of calcium ion-dependent exocytosis IDA
IDA: 通过直接分析推断
10657240 RGD
involved in positive regulation of dendritic spine development IMP
IMP: 通过突变表型推断
23889934 RGD
involved in positive regulation of endocytosis IMP
IMP: 通过突变表型推断
8294513 RGD
involved in positive regulation of late endosome to lysosome transport IMP
IMP: 通过突变表型推断
21421027 RGD
involved in positive regulation of protein secretion IMP
IMP: 通过突变表型推断
8294513 RGD
involved in positive regulation of sodium ion transmembrane transport IMP
IMP: 通过突变表型推断
14563210 RGD
involved in postsynaptic actin cytoskeleton organization IDA
IDA: 通过直接分析推断
23889934 RGD
involved in postsynaptic actin cytoskeleton organization IMP
IMP: 通过突变表型推断
23889934 RGD
involved in regulation of Arp2/3 complex-mediated actin nucleation IDA
IDA: 通过直接分析推断
23889934 RGD
involved in regulation of phospholipid metabolic process IDA
IDA: 通过直接分析推断
10657240 RGD
involved in regulation of receptor internalization IDA
IDA: 通过直接分析推断
23889934 RGD
involved in synaptic vesicle budding IMP
IMP: 通过突变表型推断
9590176 RGD
involved in very-low-density lipoprotein particle assembly IMP
IMP: 通过突变表型推断
15618550 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in COPI-coated vesicle IDA
IDA: 通过直接分析推断
8496147 RGD
located in Golgi membrane IDA
IDA: 通过直接分析推断
8496147 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
23889934 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
23889934 RGD
located in late endosome IDA
IDA: 通过直接分析推断
21421027 RGD
located in peroxisomal membrane IDA
IDA: 通过直接分析推断
16100119 RGD
is active in postsynaptic density IDA
IDA: 通过直接分析推断
23889934 RGD
is active in postsynaptic density IMP
IMP: 通过突变表型推断
23889934 RGD
located in trans-Golgi network IDA
IDA: 通过直接分析推断
14684384 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ADP-ribosylation factor 1

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-112473 NAV-2729 Inhibitor 99.10% 否
HY-173280 Brefeldin A 4-O-nicotinate Inhibitor / 否
HY-P10157 ARF(1-22) / 否
HY-P10594 Myr-Arf1(2–17) / 否
HY-RS00894 ARF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-P10658 ARF1 (2-17) Inhibitor / 否
HY-RS17736 Arf1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24201 Arf1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arf1 NCBI NCBI:375
Mus musculus Arf1 NCBI NCBI:11840
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