1. Gene
  2. JMJD4 - jumonji domain containing 4 Gene

JMJD4 - jumonji domain containing 4 Gene

中文名称:含 Jumonji 域 4

种属: Homo sapiens

基因 ID: 65094 | 基因类型: protein coding

关于 JMJD4

This gene has 5 transcripts (splice variants), 195 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 7.3), adrenal (RPKM 6.8) and 25 other tissues.

功能概要

启用 2-酮戊二酸依赖性双加氧酶活性。参与翻译终止和蛋白质羟基化的正调节。位于细胞质中。 [由基因组资源联盟提供,2022 年 4 月]

Enables 2-oxoglutarate-dependent dioxygenase activity. Involved in positive regulation of translational termination and protein hydroxylation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

JMJD4 基因产物(2)

mRNA Protein Name
NM_001161465.2 NP_001154937.2 2-oxoglutarate and iron-dependent oxygenase JMJD4 isoform 2
NM_023007.3 NP_075383.3 2-oxoglutarate and iron-dependent oxygenase JMJD4 isoform 1

JMJD4 蛋白结构

Cupin_8

Cupin_8: Cupin-like domain (88 - 331)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 463 a.a.
蛋白主名 其他名称

2-oxoglutarate and iron-dependent oxygenase JMJD4

2-oxoglutarate- and Fe(II)-dependent oxygenase

关联疾病

疾病名称 别名
Intracranial Chondrosarcoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus JMJD4 VGNC VGNC:63007
Mus musculus JMJD4 MGD MGI:2144404
Rattus norvegicus JMJD4 RGD RGD:1307186
Bos taurus JMJD4 VGNC VGNC:54440
Canis familiaris JMJD4 VGNC VGNC:42188
Macaca mulatta JMJD4 VGNC VGNC:106393