2. Gene
  3. Klf15 - Kruppel-like factor 15 Gene

Klf15 - Kruppel-like factor 15 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CKLF; KKLF; hlb444; 1810013I09Rik

基因 ID: 66277 | 基因类型: protein coding

关于 Klf15

功能概要

Enables DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Involved in cardiac muscle hypertrophy in response to stress; glomerular visceral epithelial cell differentiation; and negative regulation of peptidyl-lysine acetylation. Acts upstream of or within several processes, including cellular glucose homeostasis; positive regulation of glucose import; and response to Insulin. Located in nucleus. Is expressed in several structures, including central nervous system; cranium; early conceptus; metanephros; and nose. Used to study aortic aneurysm. Orthologous to human KLF15 (Kruppel like factor 15). [provided by Alliance of Genome Resources, Apr 2022]

Klf15 基因产物(2)

mRNA Protein Name
NM_001355668.1 NP_001342597.1 Krueppel-like factor 15 isoform 2
NM_023184.4 NP_075673.1 Krueppel-like factor 15 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
12097321 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
12097321 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12097321 MGI
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
22367544 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cardiac muscle hypertrophy in response to stress IMP
IMP: 通过突变表型推断
17438289 MGI
acts upstream of or within glial cell differentiation IDA
IDA: 通过直接分析推断
19741146 MGI
acts upstream of or within intracellular glucose homeostasis IDA
IDA: 通过直接分析推断
12097321 MGI
involved in negative regulation of peptidyl-lysine acetylation IMP
IMP: 通过突变表型推断
20375365 MGI
involved in podocyte differentiation IMP
IMP: 通过突变表型推断
22493483 MGI
acts upstream of or within positive regulation of D-glucose import IDA
IDA: 通过直接分析推断
12097321 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12097321 MGI
acts upstream of or within regulation of Wnt signaling pathway IMP
IMP: 通过突变表型推断
31582141 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
31582141 MGI
involved in regulation of gene expression IMP
IMP: 通过突变表型推断
17438289 MGI
acts upstream of or within response to insulin IDA
IDA: 通过直接分析推断
12097321 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12097321 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

Krueppel-like factor 15

cardiovascular Krueppel-like factor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07336 KLF15 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18393 Klf15 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24874 Klf15 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Klf15 NCBI NCBI:28999
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