2. Gene
  3. Spc25 - SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) Gene

Spc25 - SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Spbc25; 2600017H08Rik; 2610205L13Rik

基因 ID: 66442 | 基因类型: protein coding

关于 Spc25

功能概要

This gene encodes a component of the kinetochore-associated NDC80 protein complex, which is required for the mitotic spindle checkpoint and for microtubule-kinetochore attachment. During meiosis in mouse, the protein localizes to the germinal vesicle and then is associated with the chromosomes following germinal vesicle breakdown. Knockdown of this gene in oocytes results in precocious polar body extrusion, chromosome misalignment and aberrant spindle formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Spc25 基因产物(4)

mRNA Protein Name
NM_001199123.2 NP_001186052.1 kinetochore protein Spc25 isoform 1
NM_001199124.2 NP_001186053.1 kinetochore protein Spc25 isoform 1
NM_001305800.1 NP_001292729.1 kinetochore protein Spc25 isoform 1
NM_025565.4 NP_079841.1 kinetochore protein Spc25 isoform 2
蛋白主名 其他名称

kinetochore protein Spc25

spindle pole body component 25 homolog

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13648 SPC25 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21766 Spc25 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spc25 NCBI NCBI:57405
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