1. Gene
  2. Cert1 - ceramide transporter 1 Gene

Cert1 - ceramide transporter 1 Gene

种属: Mus musculus

同用名: CERT; GPBP; Col4a3bp; 2810404O15Rik; 9230101K08Rik

基因 ID: 68018 | 基因类型: protein coding

关于 Cert1

功能概要

Enables kinase activity. Involved in ER to Golgi ceramide transport. Acts upstream of or within several processes, including ceramide metabolic process; lipid homeostasis; and mitochondrion morphogenesis. Located in cytosol and mitochondrion. Is expressed in several structures, including alimentary system; eye; nervous system; respiratory system; and urinary system. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 34. Orthologous to human CERT1 (ceramide transporter 1). [provided by Alliance of Genome Resources, Apr 2022]

Cert1 基因产物(2)

mRNA Protein Name
NM_001164222.1 NP_001157694.1 ceramide transfer protein isoform 2
NM_023420.2 NP_075909.1 ceramide transfer protein isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables kinase activity IDA
IDA: 通过直接分析推断
11007769 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ER to Golgi ceramide transport IMP
IMP: 通过突变表型推断
24642596 MGI
acts upstream of or within cell morphogenesis IMP
IMP: 通过突变表型推断
19139267 MGI
acts upstream of or within cell population proliferation IMP
IMP: 通过突变表型推断
19139267 MGI
acts upstream of or within ceramide metabolic process IMP
IMP: 通过突变表型推断
19139267 MGI
acts upstream of or within endoplasmic reticulum organization IMP
IMP: 通过突变表型推断
19139267 MGI
acts upstream of or within heart morphogenesis IMP
IMP: 通过突变表型推断
19139267 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
19139267 MGI
acts upstream of or within lipid homeostasis IMP
IMP: 通过突变表型推断
19139267 MGI
acts upstream of or within mitochondrion organization IMP
IMP: 通过突变表型推断
19139267 MGI
acts upstream of or within muscle contraction IMP
IMP: 通过突变表型推断
19139267 MGI
acts upstream of or within response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
19139267 MGI
acts upstream of or within signal transduction IMP
IMP: 通过突变表型推断
19139267 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
19139267 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
19139267 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ceramide transfer protein

START domain-containing protein 11

ceramide transport protein

collagen type IV alpha-3-binding protein

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

goodpasture antigen-binding protein

procollagen, type IV, alpha 3 (Goodpasture ant

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cert1 NCBI NCBI:10087