2. Gene
  3. Pnpt1 - polyribonucleotide nucleotidyltransferase 1 Gene

Pnpt1 - polyribonucleotide nucleotidyltransferase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Old35; PNPase; Pnptl1; 1200003F12Rik

基因 ID: 71701 | 基因类型: protein coding

关于 Pnpt1

功能概要

Predicted to enable 3'-5'-exoribonuclease activity; RNA binding activity; and polyribonucleotide nucleotidyltransferase activity. Involved in mitochondrial mRNA catabolic process; mitochondrion morphogenesis; and regulation of cellular respiration. Located in mitochondrial intermembrane space. Is expressed in central nervous system and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 70 and combined Oxidative Phosphorylation deficiency 13. Orthologous to human PNPT1 (polyribonucleotide nucleotidyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pnpt1 基因产物(1)

mRNA Protein Name
NM_027869.2 NP_082145.1 polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mitochondrial mRNA catabolic process IMP
IMP: 通过突变表型推断
20691904 MGI
involved in mitochondrion organization IMP
IMP: 通过突变表型推断
16966381 MGI
involved in regulation of cellular respiration IMP
IMP: 通过突变表型推断
16966381 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial intermembrane space IDA
IDA: 通过直接分析推断
16966381 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
16966381 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

polyribonucleotide nucleotidyltransferase 1, mitochondrial

3'-5' RNA exonuclease OLD35

PNPase 1

PNPase old-35

polynucleotide phosphorylase 1

polynucleotide phosphorylase-like protein

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10801 PNPT1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21028 Pnpt1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27545 Pnpt1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pnpt1 NCBI NCBI:87178
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