2. Gene
  3. Tmem106b - transmembrane protein 106B Gene

Tmem106b - transmembrane protein 106B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 2310036D22Rik; 5830455K21Rik; 6430519M21Rik

基因 ID: 71900 | 基因类型: protein coding

关于 Tmem106b

功能概要

Enables ATPase binding activity. Acts upstream of or within several processes, including lysosomal lumen acidification; lysosomal protein catabolic process; and positive regulation of dendrite development. Located in lysosome. Is expressed in several structures, including alimentary system; hemolymphoid system gland; integumental system; male reproductive gland or organ; and nervous system. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human TMEM106B (transmembrane protein 106B). [provided by Alliance of Genome Resources, Apr 2022]

Tmem106b 基因产物(1)

mRNA Protein Name
NM_027992.3 NP_082268.2 transmembrane protein 106B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATPase binding IPI
IPI: 通过物理相互作用推断
28728022 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within lysosomal lumen acidification IMP
IMP: 通过突变表型推断
28728022 MGI
acts upstream of or within lysosomal protein catabolic process IMP
IMP: 通过突变表型推断
28728022 MGI
acts upstream of or within lysosomal transport IMP
IMP: 通过突变表型推断
25066864 MGI
acts upstream of or within lysosome organization IMP
IMP: 通过突变表型推断
25066864 MGI
acts upstream of or within neuron cellular homeostasis IMP
IMP: 通过突变表型推断
28728022 MGI
acts upstream of or within positive regulation of dendrite development IMP
IMP: 通过突变表型推断
25066864 MGI
acts upstream of or within positive regulation of hydrolase activity IMP
IMP: 通过突变表型推断
28728022 MGI
acts upstream of or within regulation of lysosome organization IMP
IMP: 通过突变表型推断
28728022 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in lysosome IDA
IDA: 通过直接分析推断
25066864 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transmembrane protein 106B

重组 Tmem106b 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77854 TMEM106B Protein, Mouse (HEK293, Fc) Q80X71 (P119-Q275) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14646 TMEM106B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20232 Tmem106b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26739 Tmem106b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tmem106b NCBI NCBI:54664
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