1. Gene
  2. Steap2 - six transmembrane epithelial antigen of prostate 2 Gene

Steap2 - six transmembrane epithelial antigen of prostate 2 Gene

种属: Mus musculus

同用名: STMP; IPCA1; IPCA-1; STAMP1; PCANAP1; 4921538B17Rik

基因 ID: 74051 | 基因类型: protein coding

关于 Steap2

功能概要

Enables cupric reductase activity and ferric-chelate reductase (NADPH) activity. Acts upstream of or within copper ion import across plasma membrane; iron ion import across cell outer membrane; and iron ion import across plasma membrane. Located in endosome and plasma membrane. Is expressed in several structures, including brain; gut; metanephros; reproductive system; and respiratory system. Orthologous to human STEAP2 (STEAP2 metalloreductase). [provided by Alliance of Genome Resources, Apr 2022]

Steap2 基因产物(6)

mRNA Protein Name
NM_001103156.2 NP_001096626.1 metalloreductase STEAP2 isoform 1
NM_001103157.2 NP_001096627.1 metalloreductase STEAP2 isoform 1
NM_001285469.1 NP_001272398.1 metalloreductase STEAP2 isoform 1
NM_001285470.1 NP_001272399.1 metalloreductase STEAP2 isoform 1
NM_001285471.1 NP_001272400.1 metalloreductase STEAP2 isoform 2
NM_028734.5 NP_083010.2 metalloreductase STEAP2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cupric reductase (NADH) activity IDA
IDA: 通过直接分析推断
16609065 MGI
enables ferric-chelate reductase (NADPH) activity IDA
IDA: 通过直接分析推断
16609065 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within copper ion import IDA
IDA: 通过直接分析推断
16609065 MGI
acts upstream of or within copper ion import across plasma membrane IDA
IDA: 通过直接分析推断
16609065 MGI
acts upstream of or within iron ion import across cell outer membrane IDA
IDA: 通过直接分析推断
16609065 MGI
acts upstream of or within iron ion import across plasma membrane IDA
IDA: 通过直接分析推断
16609065 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endosome IDA
IDA: 通过直接分析推断
16609065 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
16609065 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

metalloreductase STEAP2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Steap2 NCBI NCBI:261729