2. Gene
  3. Bcl2l12 - BCL2-like 12 (proline rich) Gene

Bcl2l12 - BCL2-like 12 (proline rich) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Bcl-L12; Bcl2-L12; 2810475P17Rik; 5430429M05Rik

基因 ID: 75736 | 基因类型: protein coding

关于 Bcl2l12

功能概要

Enables p53 binding activity. Acts upstream of or within negative regulation of cellular senescence and negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Predicted to be located in nucleus. Is expressed in several structures, including adrenal gland; genitourinary system; gut; quadriceps femoris muscle; and respiratory system. Orthologous to human BCL2L12 (BCL2 like 12). [provided by Alliance of Genome Resources, Apr 2022]

Bcl2l12 基因产物(4)

mRNA Protein Name
NM_001403495.1 NP_001390424.1 bcl-2-like protein 12 isoform a
NM_001403496.1 NP_001390425.1 bcl-2-like protein 12 isoform a
NM_001403497.1 NP_001390426.1 bcl-2-like protein 12 isoform b
NM_029410.4 NP_083686.1 bcl-2-like protein 12 isoform b
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables p53 binding IPI
IPI: 通过物理相互作用推断
20837658 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of cellular senescence IDA
IDA: 通过直接分析推断
20837658 MGI
acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IDA
IDA: 通过直接分析推断
20837658 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

bcl-2-like protein 12

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P1889 Bim BH3, Peptide IV 99.35% 否
HY-149622 Bcl-2-IN-12 Inhibitor / 否
HY-P1889A Bim BH3, Peptide IV TFA / 否
HY-RS01430 BCL2L12 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21989 Bcl2l12 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28507 Bcl2l12 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bcl2l12 NCBI NCBI:83596
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