1. Gene
  2. Brsk2 - BR serine/threonine kinase 2 Gene

Brsk2 - BR serine/threonine kinase 2 Gene

种属: Mus musculus

同用名: SADA; SAD-A; 4833424K13Rik

基因 ID: 75770 | 基因类型: protein coding

关于 Brsk2

功能概要

Enables protein kinase binding activity; protein serine/threonine kinase activity; and tau-protein kinase activity. Involved in several processes, including microtubule Cytoskeleton organization involved in establishment of planar polarity; regulation of axonogenesis; and regulation of Insulin secretion involved in cellular response to glucose stimulus. Acts upstream of or within neuron projection morphogenesis and peptidyl-serine phosphorylation. Predicted to be located in distal axon and endoplasmic reticulum. Predicted to be active in centrosome and cytoplasm. Is expressed in several structures, including central nervous system and retina. Orthologous to human BRSK2 (BR serine/threonine kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Brsk2 基因产物(4)

mRNA Protein Name
NM_001009929.3 NP_001009929.1 serine/threonine-protein kinase BRSK2 isoform beta
NM_001009930.3 NP_001009930.1 serine/threonine-protein kinase BRSK2 isoform gamma
NM_001276763.1 NP_001263692.1 serine/threonine-protein kinase BRSK2 isoform delta
NM_029426.2 NP_083702.1 serine/threonine-protein kinase BRSK2 isoform alpha
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20026642 MGI
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
17482548 MGI
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
15705853 MGI
enables tau-protein kinase activity IDA
IDA: 通过直接分析推断
15705853 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in axonogenesis IMP
IMP: 通过突变表型推断
17482548 MGI
acts upstream of or within establishment of cell polarity IGI
IGI: 通过遗传相互作用推断
15705853 MGI
involved in establishment of cell polarity IGI
IGI: 通过遗传相互作用推断
15705853 MGI
involved in establishment of cell polarity IMP
IMP: 通过突变表型推断
17482548 MGI
involved in microtubule cytoskeleton organization involved in establishment of planar polarity IGI
IGI: 通过遗传相互作用推断
18268107 MGI
acts upstream of or within neuron differentiation IGI
IGI: 通过遗传相互作用推断
15705853 MGI
involved in neuron differentiation IGI
IGI: 通过遗传相互作用推断
15705853 MGI
acts upstream of or within neuron projection morphogenesis IGI
IGI: 通过遗传相互作用推断
20026642 MGI
acts upstream of or within peptidyl-serine phosphorylation IDA
IDA: 通过直接分析推断
20026642 MGI
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
15705853 MGI
involved in regulation of axonogenesis IGI
IGI: 通过遗传相互作用推断
18268107 MGI
involved in regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
22798068 MGI
involved in regulation of neuron projection development IGI
IGI: 通过遗传相互作用推断
18268107 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

serine/threonine-protein kinase BRSK2

BR serine/threonine-protein kinase 2

brain-specific serine/threonine-protein kinase 2

serine/threonine-protein kinase SAD-A

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Brsk2 NCBI NCBI:9024