2. Gene
  3. ZNF154 - zinc finger protein 154 Gene

ZNF154 - zinc finger protein 154 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品

中文名称：锌指蛋白 154

种属: Homo sapiens

同用名: pHZ-92

基因 ID: 7710 | 基因类型: protein coding

关于 ZNF154

Cytogenetic location: 19q13.43 Genomic coordinates (GRCh38): 19:57,696,275-57,709,204 (from NCBI)

This gene has 3 transcripts (splice variants), 163 orthologues and 38 paralogues. Ubiquitous expression in thyroid (RPKM 3.0), spleen (RPKM 2.6) and 24 other tissues.

功能概要

该基因编码的蛋白质属于转录调节因子锌指 Kruppel 家族，其成员被认为在正常和异常细胞生长和分化中发挥作用。该基因的超甲基化与非肌肉浸润性膀胱癌的复发有关。可变剪接导致多个转录本变体。[RefSeq 提供，2014 年 3 月]

This gene encodes a protein that belongs to the zinc finger Kruppel family of transcriptional regulators, whose members are thought to function in normal and abnormal cell growth and differentiation. Hypermethylation of this gene is associated with the recurrence of non muscle invasive bladder Cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

ZNF154 基因产物(1)

mRNA Protein Name
NM_001085384.3 NP_001078853.1 zinc finger protein 154

ZNF154 蛋白结构

KRAB

KRAB: KRAB box (14 - 54)

zf-C2H2_6

zf-C2H2_6: C2H2-type zinc finger (161 - 171)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (176 - 199)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (204 - 228)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (231 - 255)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (259 - 284)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (288 - 311)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (316 - 339)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (343 - 366)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (371 - 395)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (400 - 424)

  • 0
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  • 437 a.a.
蛋白主名 其他名称

zinc finger protein 154

关联疾病

疾病名称 别名
Gastric Papillary Adenocarcinoma

Papillary Adenocarcinoma Of Stomach
Gastric Tubular Adenocarcinoma

Tubular Adenocarcinoma Of Stomach
Bladder Cancer

Urinary Bladder Cancer

Bladder Carcinoma

Urinary Bladder Carcinoma

Bladder Neoplasm

Bladder Tumor

Cancer, Bladder

Malignant Neoplasm Of Urinary Bladder

Carcinoma Of Bladder

Bladder Cancer, Somatic

Tumor Of The Bladder

Carcinoma Of Urinary Bladder

Bladder Carcinoma Urinary

Cancer Of The Urinary Bladder

Cancer, Urinary Bladder

Malignant Bladder Neoplasm

Malignant Bladder Tumor

Neoplasm Of The Bladder

Neoplasm Of The Urinary Bladder

Tumor Of The Urinary Bladder

Urinary Bladder Neoplasm

BLC

Urothelial Carcinoma Of The Bladder

Bladder Tumors

Urinary Bladder Neoplasms

Bladder Cancer Nos

Vesical Cancer Nos

Malignant Neoplasm Of Bladder, Part Unspecified

Malignant Tumour Of Urinary Bladder

Primary Malignant Neoplasm Of Bladder
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16105 ZNF154 Human Pre-designed siRNA Set A Pre-designed Set / 否
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