1. Gene
  2. MCTP1 - multiple C2 and transmembrane domain containing 1 Gene

MCTP1 - multiple C2 and transmembrane domain containing 1 Gene

中文名称:含多个 C2 和跨膜域 1

种属: Homo sapiens

基因 ID: 79772 | 基因类型: protein coding

关于 MCTP1

Cytogenetic location: 5q15 Genomic coordinates (GRCh38): 5:94,703,690-95,285,094 (from NCBI)

This gene has 18 transcripts (splice variants), 270 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 4.3), fat (RPKM 3.5) and 22 other tissues.

功能概要

启用钙离子结合活性。预计参与多个过程,包括调节化学突触传递;内吞作用的负调节;和对氧化应激反应的负调节。是膜的组成部分。 [由基因组资源联盟提供,2022 年 4 月]

Enables calcium ion binding activity. Predicted to be involved in several processes, including modulation of chemical synaptic transmission; negative regulation of endocytosis; and negative regulation of response to oxidative stress. Is integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

MCTP1 基因产物(20)

mRNA Protein Name
NM_001002796.5 NP_001002796.1 multiple C2 and transmembrane domain-containing protein 1 isoform S
NM_001297777.3 NP_001284706.1 multiple C2 and transmembrane domain-containing protein 1 isoform 3
NM_001393535.1 NP_001380464.1 multiple C2 and transmembrane domain-containing protein 1 isoform 4
NM_001393536.1 NP_001380465.1 multiple C2 and transmembrane domain-containing protein 1 isoform 5
NM_001393537.1 NP_001380466.1 multiple C2 and transmembrane domain-containing protein 1 isoform 6
NM_001393538.1 NP_001380467.1 multiple C2 and transmembrane domain-containing protein 1 isoform 7
NM_001393539.1 NP_001380468.1 multiple C2 and transmembrane domain-containing protein 1 isoform 8
NM_001393540.1 NP_001380469.1 multiple C2 and transmembrane domain-containing protein 1 isoform 9
NM_001393541.1 NP_001380470.1 multiple C2 and transmembrane domain-containing protein 1 isoform 10
NM_001393542.1 NP_001380471.1 multiple C2 and transmembrane domain-containing protein 1 isoform 11
NM_001393543.1 NP_001380472.1 multiple C2 and transmembrane domain-containing protein 1 isoform 12
NM_001393544.1 NP_001380473.1 multiple C2 and transmembrane domain-containing protein 1 isoform 13
NM_001393545.1 NP_001380474.1 multiple C2 and transmembrane domain-containing protein 1 isoform 14
NM_001393546.1 NP_001380475.1 multiple C2 and transmembrane domain-containing protein 1 isoform 15
NM_001393547.1 NP_001380476.1 multiple C2 and transmembrane domain-containing protein 1 isoform 16
NM_001393548.1 NP_001380477.1 multiple C2 and transmembrane domain-containing protein 1 isoform 17
NM_001393549.1 NP_001380478.1 multiple C2 and transmembrane domain-containing protein 1 isoform 18
NM_001393550.1 NP_001380479.1 multiple C2 and transmembrane domain-containing protein 1 isoform 19
NM_001393551.1 NP_001380480.1 multiple C2 and transmembrane domain-containing protein 1 isoform 20
NM_024717.7 NP_078993.4 multiple C2 and transmembrane domain-containing protein 1 isoform L
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
15528213 GOA
NOT enables calcium-dependent phospholipid binding IDA
IDA: 通过直接分析推断
15528213 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
15528213 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

MCTP1 蛋白结构

C2

C2: C2 domain (263 - 343)

C2

C2: C2 domain (473 - 553)

C2

C2: C2 domain (628 - 707)

PRT_C

PRT_C: Plant phosphoribosyltransferase C-terminal (872 - 974)

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  • 999 a.a.
蛋白主名 其他名称

multiple C2 and transmembrane domain-containing protein 1

multiple C2 domains, transmembrane 1

直系同源

种属 基因名 来源 基因 ID
Mus musculus MCTP1 MGD MGI:1926021
Canis familiaris MCTP1 VGNC VGNC:43094
Macaca mulatta MCTP1 VGNC VGNC:74589
Rattus norvegicus MCTP1 RGD RGD:1305199
Bos taurus MCTP1 VGNC VGNC:106816
Felis catus MCTP1 VGNC VGNC:97503