2. Gene
  3. Mlh1 - mutL homolog 1 Gene

Mlh1 - mutL homolog 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 81685 | 基因类型: protein coding

关于 Mlh1

功能概要

Predicted to enable several functions, including ATP hydrolysis activity; chromatin binding activity; and guanine/thymine mispair binding activity. Predicted to contribute to MutSalpha complex binding activity and single-stranded DNA binding activity. Involved in several processes, including response to hypoxia; response to toxic substance; and spermatogenesis. Located in synaptonemal complex. Used to study lung carcinoma. Human ortholog(s) of this gene implicated in Lynch syndrome (multiple); gastrointestinal system Cancer (multiple); lung cancer; mismatch repair Cancer syndrome; and sporadic breast Cancer. Orthologous to human MLH1 (mutL homolog 1). [provided by Alliance of Genome Resources, Apr 2022]

Mlh1 基因产物(1)

mRNA Protein Name
NM_031053.2 NP_112315.2 DNA mismatch repair protein Mlh1
蛋白主名 其他名称

DNA mismatch repair protein Mlh1

mismatch repair protein 1

mutL homolog 1, colon cancer, nonpolyposis type 2

mutL protein homolog 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08489 MLH1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19146 Mlh1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25637 Mlh1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mlh1 NCBI NCBI:4292
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