1. Gene
  2. Ntf3 - neurotrophin 3 Gene

Ntf3 - neurotrophin 3 Gene

种属: Rattus norvegicus

基因 ID: 81737 | 基因类型: protein coding

关于 Ntf3

功能概要

Enables nerve growth factor binding activity. Involved in modulation of chemical synaptic transmission; nervous system development; and response to immobilization stress. Predicted to be located in cytoplasmic vesicle. Predicted to be active in several cellular components, including axon; dendrite; and synaptic vesicle. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in Alzheimer's disease and asthma. Orthologous to human NTF3 (neurotrophin 3). [provided by Alliance of Genome Resources, Apr 2022]

Ntf3 基因产物(4)

mRNA Protein Name
NM_001270868.1 NP_001257797.1 neurotrophin-3 isoform 2
NM_001270869.1 NP_001257798.1 neurotrophin-3 isoform 1
NM_001270870.1 NP_001257799.1 neurotrophin-3 isoform 3 precursor
NM_031073.3 NP_112335.3 neurotrophin-3 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables nerve growth factor binding IMP
IMP: 通过突变表型推断
2164684 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
14507970 RGD
involved in myelination IDA
IDA: 通过直接分析推断
15139015 RGD
involved in nervous system development IMP
IMP: 通过突变表型推断
2164684 RGD
involved in positive regulation of glial cell differentiation IDA
IDA: 通过直接分析推断
15139015 RGD
involved in response to immobilization stress IEP
IEP: 通过表达模式推断
7568018 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

neurotrophin-3

HDNF

NGF-2

NT-3

nerve growth factor 2

neurotrophic factor

neurotrophin-3 (HDNF/NT-3)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ntf3 NCBI NCBI:4908