1. Gene
  2. TATDN1 - TatD DNase domain containing 1 Gene

TATDN1 - TatD DNase domain containing 1 Gene

中文名称:含 TatD DNase 域 1

种属: Homo sapiens

同用名: CDA11

基因 ID: 83940 | 基因类型: protein coding

关于 TATDN1

Cytogenetic location: 8q24.13 Genomic coordinates (GRCh38): 8:124,488,494-124,539,088 (from NCBI)

This gene has 21 transcripts (splice variants), 201 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 16.0), ovary (RPKM 13.3) and 25 other tissues.

功能概要

预测启用 3'-5'-外脱氧核糖核酸酶活性。预测参与 DNA 代谢过程和核酸磷酸二酯键的水解。位于核质中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable 3'-5'-exodeoxyribonuclease activity. Predicted to be involved in DNA metabolic process and nucleic acid phosphodiester bond hydrolysis. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TATDN1 基因产物(5)

mRNA Protein Name
NM_001146160.1 NP_001139632.1 deoxyribonuclease TATDN1 isoform b
NM_001317889.1 NP_001304818.1 deoxyribonuclease TATDN1 isoform c
NM_001317890.1 NP_001304819.1 deoxyribonuclease TATDN1 isoform d
NM_001317891.1 NP_001304820.1 deoxyribonuclease TATDN1 isoform e
NM_032026.4 NP_114415.1 deoxyribonuclease TATDN1 isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15846844 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

TATDN1 蛋白结构

TatD_DNase

TatD_DNase: TatD related DNase (7 - 293)

  • 0
  • 100
  • 200
  • 297 a.a.
蛋白主名 其他名称

deoxyribonuclease TATDN1

hepatocarcinoma high expression protein

关联疾病

疾病名称 别名
Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Non-Invasive Bladder Urothelial Carcinoma

Stage 0 Bladder Urothelial Carcinoma

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus TATDN1 RGD RGD:1585145
Mus musculus TATDN1 MGD MGI:1916944
Bos taurus TATDN1 VGNC VGNC:35617
Macaca mulatta TATDN1 VGNC VGNC:104498
Canis familiaris TATDN1 VGNC VGNC:47123