2. Gene
  3. Grip1 - glutamate receptor interacting protein 1 Gene

Grip1 - glutamate receptor interacting protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 84016 | 基因类型: protein coding

关于 Grip1

功能概要

Enables signaling receptor binding activity. Involved in dendrite arborization; positive regulation of neuron projection arborization; and protein transport. Located in neuronal cell body. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in Fraser syndrome 3. Orthologous to human GRIP1 (glutamate receptor interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Grip1 基因产物(1)

mRNA Protein Name
NM_032069.1 NP_114458.1 glutamate receptor-interacting protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase binding IPI
IPI: 通过物理相互作用推断
21847098 RGD
enables PDZ domain binding IPI
IPI: 通过物理相互作用推断
17084383 RGD
enables ionotropic glutamate receptor binding IDA
IDA: 通过直接分析推断
11007883 RGD
enables ionotropic glutamate receptor binding IPI
IPI: 通过物理相互作用推断
10896157 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9647694 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
21847098 RGD
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
16037816 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to brain-derived neurotrophic factor stimulus IDA
IDA: 通过直接分析推断
14597197 RGD
involved in cellular response to phorbol 13-acetate 12-myristate IDA
IDA: 通过直接分析推断
11007883 RGD
involved in cerebral cortex development IEP
IEP: 通过表达模式推断
14597197 RGD
involved in dendrite arborization IMP
IMP: 通过突变表型推断
15965473 RGD
involved in negative regulation of AMPA receptor activity IMP
IMP: 通过突变表型推断
12597860 RGD
involved in nervous system development IMP
IMP: 通过突变表型推断
11931740 RGD
involved in positive regulation of dendrite morphogenesis IMP
IMP: 通过突变表型推断
15965473 RGD
involved in positive regulation of neuron projection arborization IGI
IGI: 通过遗传相互作用推断
25424568 RGD
involved in positive regulation of neuron projection arborization IMP
IMP: 通过突变表型推断
15965473 RGD
involved in positive regulation of protein localization to plasma membrane IDA
IDA: 通过直接分析推断
17207582 RGD
involved in regulation of kainate selective glutamate receptor activity IMP
IMP: 通过突变表型推断
12597860 RGD
involved in regulation of synaptic scaling IMP
IMP: 通过突变表型推断
26109571 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in GABA-ergic synapse IDA
IDA: 通过直接分析推断
15226318 RGD
located in dendrite IDA
IDA: 通过直接分析推断
15912503 RGD
located in dendritic shaft IDA
IDA: 通过直接分析推断
17626212 RGD
located in dendritic spine IDA
IDA: 通过直接分析推断
17626212 RGD
located in dendritic spine head IDA
IDA: 通过直接分析推断
11007883 RGD
located in dendritic spine neck IDA
IDA: 通过直接分析推断
11007883 RGD
part of exocyst IDA
IDA: 通过直接分析推断
26109571 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
10436050 RGD
located in glutamatergic synapse IDA
IDA: 通过直接分析推断
15226318 RGD
located in microtubule IDA
IDA: 通过直接分析推断
15226318 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
1041498 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
15226318 RGD
is active in postsynapse IDA
IDA: 通过直接分析推断
9069286 RGD
located in postsynapse IDA
IDA: 通过直接分析推断
18315564 RGD
is active in postsynaptic density IDA
IDA: 通过直接分析推断
10436050 RGD
located in postsynaptic membrane IDA
IDA: 通过直接分析推断
15226318 RGD
located in presynapse IDA
IDA: 通过直接分析推断
26109571 RGD
located in presynaptic active zone IDA
IDA: 通过直接分析推断
15912503 RGD
located in presynaptic membrane IDA
IDA: 通过直接分析推断
15226318 RGD
located in proximal dendrite IDA
IDA: 通过直接分析推断
11978826 RGD
located in recycling endosome IDA
IDA: 通过直接分析推断
20956289 RGD
located in spine synapse IDA
IDA: 通过直接分析推断
11007883 RGD
located in synaptic cleft IDA
IDA: 通过直接分析推断
26109571 RGD
located in synaptic membrane IDA
IDA: 通过直接分析推断
15912503 RGD
located in terminal bouton IDA
IDA: 通过直接分析推断
15226318 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

glutamate receptor-interacting protein 1

AMPA receptor-interacting protein GRIP1

GRIP-1

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05809 GRIP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09090 NCOA2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19007 Grip1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19721 Ncoa2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25496 Grip1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26217 Ncoa2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Grip1 NCBI NCBI:23426
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