2. Gene
  3. Kcnq1 - potassium voltage-gated channel subfamily Q member 1 Gene

Kcnq1 - potassium voltage-gated channel subfamily Q member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Kvlqt1

基因 ID: 84020 | 基因类型: protein coding

关于 Kcnq1

功能概要

Enables delayed rectifier Potassium Channel activity; identical protein binding activity; and outward rectifier Potassium Channel activity. Involved in several processes, including male gonad development; regulation of secretion; and response to anesthetic. Located in basolateral plasma membrane; sarcolemma; and zymogen granule membrane. Is integral component of plasma membrane. Part of voltage-gated Potassium Channel complex. Used to study hypertension and long QT syndrome. Human ortholog(s) of this gene implicated in heart conduction disease (multiple) and long QT syndrome (multiple). Orthologous to human KCNQ1 (potassium voltage-gated channel subfamily Q member 1). [provided by Alliance of Genome Resources, Apr 2022]

Kcnq1 基因产物(1)

mRNA Protein Name
NM_032073.2 NP_114462.2 potassium voltage-gated channel subfamily KQT member 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables delayed rectifier potassium channel activity IDA
IDA: 通过直接分析推断
11220365 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
20962273 RGD
enables outward rectifier potassium channel activity IDA
IDA: 通过直接分析推断
11220365 RGD
enables potassium channel activity IDA
IDA: 通过直接分析推断
11804849 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15389592 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intestinal absorption IMP
IMP: 通过突变表型推断
16314573 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
15389592 RGD
involved in negative regulation of insulin secretion IDA
IDA: 通过直接分析推断
16133261 RGD
involved in potassium ion transport IDA
IDA: 通过直接分析推断
16133261 RGD
involved in regulation of membrane potential IDA
IDA: 通过直接分析推断
11804849 RGD
involved in response to anesthetic IDA
IDA: 通过直接分析推断
12616988 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
15843438 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
14670813 RGD
part of voltage-gated potassium channel complex IDA
IDA: 通过直接分析推断
15389592 RGD
located in zymogen granule membrane IDA
IDA: 通过直接分析推断
18216164 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

potassium voltage-gated channel subfamily KQT member 1

IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1

KQT-like 1

potassium channel, voltage-gated KQT-like subfamily Q, member 1

potassium voltage-gated channel, KQT-like subfamily, member 1

voltage-gated potassium channel subunit Kv

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-12637 Hexachlorophene 99.66% 否
Pre-clinical Phase
生物活性分子 (15)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108577 XE991 dihydrochloride Inhibitor 99.63% 否
HY-12343 ML277 Activator 98.46% 否
HY-17442 Azathramycin Inhibitor 99.85% 否
HY-108591 L-364,373 Activator 99.67% 否
HY-108587 ICA 110381 Modulator 99.85% 否
HY-18063 ML252 Inhibitor 99.9% 否
HY-145992 KCNQ1 activator-1 Activator 99.03% 否
HY-108577A XE991 Inhibitor 99.62% 否
HY-121520 Docosahexaenoyl glycine Activator / 否
HY-122504 Linoleoyl glycine Inhibitor / 否
HY-RS07173 KCNQ1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-121977 IKs124 Inhibitor / 否
HY-18063A ML252 hydrochloride Inhibitor / 否
HY-RS18286 Kcnq1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24764 Kcnq1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kcnq1 NCBI NCBI:3784
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