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  2. NTPCR - nucleoside-triphosphatase, cancer-related Gene

NTPCR - nucleoside-triphosphatase, cancer-related Gene

中文名称:核苷三磷酸酶,癌症相关

种属: Homo sapiens

同用名: THEP1; C1orf57; HCR-NTPase

基因 ID: 84284 | 基因类型: protein coding

关于 NTPCR

This gene has 8 transcripts (splice variants) and 198 orthologues. Ubiquitous expression in brain (RPKM 18.5), kidney (RPKM 18.3) and 25 other tissues.

功能概要

该基因编码的蛋白质是一种非特异性核苷三磷酸酶,在体外作用缓慢。该基因在许多肿瘤组织中过度表达,虽然它对细胞不是必需的,但过度表达具有细胞毒性。然而,细胞毒性与其三磷酸酶活性无关。[RefSeq 提供,2016 年 7 月]

The protein encoded by this gene is a non-specific nucleoside triphosphatase that is slow-acting in vitro. This gene is overexpressed in many tumor tissues, and while it is not essential for the cell, overexpression is cytotoxic. However, the cytotoxicity is not related to its triphosphatase activity. [provided by RefSeq, Jul 2016]

NTPCR 基因产物(3)

mRNA Protein Name
NM_001329452.2 NP_001316381.1 cancer-related nucleoside-triphosphatase isoform 2
NM_001329453.2 NP_001316382.1 cancer-related nucleoside-triphosphatase isoform 3
NM_032324.3 NP_115700.1 cancer-related nucleoside-triphosphatase isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ribonucleoside triphosphate phosphatase activity IMP
IMP: 通过突变表型推断
17291528 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

NTPCR 蛋白结构

NTPase_1

NTPase_1: NTPase (4 - 181)

  • 0
  • 100
  • 190 a.a.
蛋白主名 其他名称

cancer-related nucleoside-triphosphatase

human cancer-related NTPase

NTPCR 抗体

目录号 产品名 应用 反应物种
HY-P81699 NTPCR Antibody (YA1444) WB, IP Human

关联疾病

疾病名称 别名
Blackwater Fever

Black Water Fever

Hemoglobinuric, Malaria

Malarial Hemoglobinuria

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus NTPCR RGD RGD:1306192
Mus musculus NTPCR MGD MGI:1913816