1. Gene
  2. ZBED3 - zinc finger BED-type containing 3 Gene

ZBED3 - zinc finger BED-type containing 3 Gene

中文名称:含锌指 BED 型 3

种属: Homo sapiens

基因 ID: 84327 | 基因类型: protein coding

关于 ZBED3

Cytogenetic location: 5q13.3 Genomic coordinates (GRCh38): 5:77,072,072-77,087,285 (from NCBI)

This gene has 3 transcripts (splice variants) and 51 orthologues. Ubiquitous expression in fat (RPKM 5.0), kidney (RPKM 4.8) and 25 other tissues.

功能概要

该基因属于一类通过 hAT DNA 转座产生并编码调节蛋白的基因。该基因在肺癌组织中被上调,其中编码的蛋白质导致 β-连环蛋白的积累和增强的肺癌细胞侵袭。此外,编码的蛋白质可以分泌并参与胰岛素抵抗。[RefSeq 提供,2016 年 7 月]

This gene belongs to a class of genes that arose through hAT DNA transposition and that encode regulatory proteins. This gene is upregulated in lung Cancer tissues, where the encoded protein causes an accumulation of beta-catenin and enhanced lung Cancer cell invasion. In addition, the encoded protein can be secreted and be involved in resistance to Insulin. [provided by RefSeq, Jul 2016]

ZBED3 基因产物(2)

mRNA Protein Name
NM_001329564.2 NP_001316493.1 zinc finger BED domain-containing protein 3
NM_032367.4 NP_115743.1 zinc finger BED domain-containing protein 3
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to glucose IDA
IDA: 通过直接分析推断
24283382 GOA
involved in response to insulin IDA
IDA: 通过直接分析推断
24283382 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
24283382 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ZBED3 蛋白结构

zf-BED

zf-BED: BED zinc finger (46 - 98)

  • 0
  • 100
  • 200
  • 234 a.a.
蛋白主名 其他名称

zinc finger BED domain-containing protein 3

2610005H11Rik

关联疾病

疾病名称 别名
Maturity-Onset Diabetes Of The Young

MODY

Maturity Onset Diabetes Mellitus In Young

Mason-Type Diabetes

Mason Type Diabetes

Maturity Onset Diabetes Of The Young

Mody Syndrome

Diabetes Of The Young, Maturity-Onset

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus ZBED3 VGNC VGNC:107034
Rattus norvegicus ZBED3 RGD RGD:1309665
Macaca mulatta ZBED3 VGNC VGNC:79271
Felis catus ZBED3 VGNC VGNC:102365
Mus musculus ZBED3 MGD MGI:1919364