2. Gene
  3. Bnip3 - BCL2 interacting protein 3 Gene

Bnip3 - BCL2 interacting protein 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 84480 | 基因类型: protein coding

关于 Bnip3

功能概要

Enables identical protein binding activity. Involved in several processes, including cardiac muscle cell apoptotic process; central nervous system development; and positive regulation of cell death. Located in dendrite; mitochondrion; and nucleoplasm. Used to study congestive heart failure. Biomarker of several diseases, including cerebrovascular disease (multiple); chronic obstructive pulmonary disease; end stage renal disease; obesity; and retinal detachment. Orthologous to human BNIP3 (BCL2 interacting protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Bnip3 基因产物(1)

mRNA Protein Name
NM_053420.3 NP_445872.1 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
25436615 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
25436615 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in autophagic cell death IMP
IMP: 通过突变表型推断
19539716 RGD
involved in cardiac muscle cell apoptotic process IMP
IMP: 通过突变表型推断
12226479 RGD
involved in cellular response to hydrogen peroxide IEP
IEP: 通过表达模式推断
28661226 RGD
involved in cellular response to hydrogen peroxide IMP
IMP: 通过突变表型推断
19539716 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
17379825 RGD
involved in cerebral cortex development IEP
IEP: 通过表达模式推断
16765336 RGD
involved in negative regulation of mitochondrial membrane permeability involved in apoptotic process IMP
IMP: 通过突变表型推断
17980495 RGD
involved in negative regulation of mitochondrial membrane potential IMP
IMP: 通过突变表型推断
17980495 RGD
involved in neuron apoptotic process IDA
IDA: 通过直接分析推断
14972662 RGD
involved in oligodendrocyte differentiation IEP
IEP: 通过表达模式推断
12787069 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
16645637 RGD
involved in positive regulation of autophagy of mitochondrion IMP
IMP: 通过突变表型推断
23698117 RGD
involved in positive regulation of cardiac muscle cell apoptotic process IDA
IDA: 通过直接分析推断
23028672 RGD
involved in positive regulation of mitochondrial calcium ion concentration IMP
IMP: 通过突变表型推断
25489073 RGD
involved in response to axon injury IEP
IEP: 通过表达模式推断
22639046 RGD
involved in response to hyperoxia IEP
IEP: 通过表达模式推断
20157446 RGD
involved in response to hypoxia IDA
IDA: 通过直接分析推断
14972662 RGD
involved in response to oxygen-glucose deprivation IEP
IEP: 通过表达模式推断
22639046 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
14972662 RGD
located in dendrite IDA
IDA: 通过直接分析推断
14972662 RGD
located in nucleoplasm IDA
IDA: 通过直接分析推断
14972662 RGD
located in nucleus IDA
IDA: 通过直接分析推断
14972662 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

BCL2/adenovirus E1B 19 kDa-interacting protein 3

BCL2/adenovirus E1B interacting protein 3

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01564 BNIP3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-121859 RU28362 Agonist / 否
HY-RS01565 BNIP3L Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16291 Bnip3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18697 Bnip3l Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23202 Bnip3 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25184 Bnip3l Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bnip3 NCBI NCBI:664
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