1. Gene
  2. Angpt1 - angiopoietin 1 Gene

Angpt1 - angiopoietin 1 Gene

种属: Rattus norvegicus

同用名: Agpt; Agpt1; Ang-1

基因 ID: 89807 | 基因类型: protein coding

关于 Angpt1

功能概要

Enables identical protein binding activity. Involved in several processes, including animal organ development; response to estrogen; and response to vitamin B3. Located in extracellular space. Biomarker of gastric ulcer; in situ carcinoma; myocardial infarction; nephrosis; and pulmonary hypertension. Human ortholog(s) of this gene implicated in brain ischemia; diabetic retinopathy; and hypertension. Orthologous to human ANGPT1 (angiopoietin 1). [provided by Alliance of Genome Resources, Apr 2022]

Angpt1 基因产物(1)

mRNA Protein Name
NM_053546.2 NP_445998.2 angiopoietin-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
15056293 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
16437624 RGD
involved in glomerulus vasculature development IMP
IMP: 通过突变表型推断
20056745 RGD
involved in liver regeneration IEP
IEP: 通过表达模式推断
11549276 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
17989359 RGD
involved in ovarian follicle development IMP
IMP: 通过突变表型推断
17989359 RGD
involved in response to estrogen IEP
IEP: 通过表达模式推断
15637314 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
11129953 RGD
involved in response to vitamin B3 IEP
IEP: 通过表达模式推断
17557352 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
15056293 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

angiopoietin-1

重组 Angpt1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P700560 ANGPT1/Angiopoietin-1, Rat (P. pastoris, His) O35460 (S20-F497) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Angpt1 NCBI NCBI:284
Macaca fascicularis Angpt1 NCBI NCBI:102123994
Mus musculus Angpt1 NCBI NCBI:11600