1. Gene
  2. Tnfsf4 - TNF superfamily member 4 Gene

Tnfsf4 - TNF superfamily member 4 Gene

种属: Rattus norvegicus

同用名: Ox40l; Tnlg2b

基因 ID: 89814 | 基因类型: protein coding

关于 Tnfsf4

功能概要

Enables tumor necrosis factor receptor superfamily binding activity. Involved in T cell proliferation; positive regulation of activated T cell proliferation; and positive regulation of interleukin-2 production. Located in cell surface. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human TNFSF4 (TNF Superfamily member 4). [provided by Alliance of Genome Resources, Apr 2022]

Tnfsf4 基因产物(1)

mRNA Protein Name
NM_053552.2 NP_446004.1 tumor necrosis factor ligand superfamily member 4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables tumor necrosis factor receptor superfamily binding IMP
IMP: 通过突变表型推断
10772947 RGD
enables tumor necrosis factor receptor superfamily binding IPI
IPI: 通过物理相互作用推断
9790919 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T cell proliferation IMP
IMP: 通过突变表型推断
10772947 RGD
involved in positive regulation of activated T cell proliferation IDA
IDA: 通过直接分析推断
9790919 RGD
involved in positive regulation of interleukin-2 production IDA
IDA: 通过直接分析推断
9790919 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
9790919 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tumor necrosis factor ligand superfamily member 4

OX40 ligand

tumor necrosis factor (ligand) superfamily, member 4

tumor necrosis factor ligand 2b

tumor necrosis factor superfamily member 4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnfsf4 NCBI NCBI:7292
Macaca fascicularis Tnfsf4 NCBI NCBI:102141877
Mus musculus Tnfsf4 NCBI NCBI:22164
Leporidae Tnfsf4 NCBI
Macaca mulatta Tnfsf4 NCBI NCBI:706255