2. Gene
  3. GTPBP1 - GTP binding protein 1 Gene

GTPBP1 - GTP binding protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：GTP 结合蛋白 1

种属: Homo sapiens

同用名: GP1; GP-1; HSPC018

基因 ID: 9567 | 基因类型: protein coding

关于 GTPBP1

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:38,705,944-38,743,115 (from NCBI)

This gene has 13 transcripts (splice variants), 204 orthologues and 18 paralogues. Ubiquitous expression in bone marrow (RPKM 26.4), spleen (RPKM 10.5) and 25 other tissues.

功能概要

该基因被干扰素-γ 上调，并编码一种蛋白质，该蛋白质是 GTP 结合蛋白 AGP11/GTPBP1 家族的成员。在小鼠中发现了一种结构相似的蛋白质，该蛋白质基因的破坏没有可观察到的表型。[RefSeq 提供，2008 年 7 月]

This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. [provided by RefSeq, Jul 2008]

GTPBP1 基因产物(1)

mRNA Protein Name
NM_004286.5 NP_004277.2 GTP-binding protein 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase activity IDA
IDA: 通过直接分析推断
30108131 GOA
enables alpha-aminoacyl-tRNA binding IDA
IDA: 通过直接分析推断
30108131 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables tRNA binding IDA
IDA: 通过直接分析推断
30108131 GOA
enables translation elongation factor activity IDA
IDA: 通过直接分析推断
30108131 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cytoplasmic translation IDA
IDA: 通过直接分析推断
30108131 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GTPBP1 蛋白结构

GTP_EFTU

GTP_EFTU: Elongation factor Tu GTP binding domain (161 - 383)

GTP_EFTU_D2

GTP_EFTU_D2: Elongation factor Tu domain 2 (409 - 479)

GTP_EFTU_D3

GTP_EFTU_D3: Elongation factor Tu C-terminal domain (486 - 573)

  • 0
  • 200
  • 400
  • 600
  • 669 a.a.
蛋白主名 其他名称

GTP-binding protein 1

G-protein 1

GTPBP1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
GTPBP1 O00178 C7orf25 Homo sapiens Q9BPX7
Validated Y2H
32296183
种属内
GTPBP1 O00178 C7orf25 Homo sapiens Q9BPX7
Y2H Prey Pooling
32296183
种属内
GTPBP1 O00178 C7orf25 Homo sapiens Q9BPX7
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Argentine Hemorrhagic Fever

Argentinian Hemorrhagic Fever

Junin Hemorrhagic Fever

Hemorrhagic Fever, Argentinian

Ahf - [Argentinian Haemorrhagic Fever]

Argentine Haemorrhagic Fever

Junin Haemorrhagic Fever
Bolivian Hemorrhagic Fever

Machupo Hemorrhagic Fever

Hemorrhagic Fever, Bolivian

Bhf - [Bolivian Haemorrhagic Fever]

Machupo Haemorrhagic Fever
Marburg Hemorrhagic Fever

Marburg Virus Disease

Marburg Disease

Green Monkey Disease

Mhf

Vervet Monkey Disease

Mard - [Marburg Disease]

Mvd - [Marburg Virus Disease]

Marburg Haemorrhagic Fever

Mhf - [Marburg Haemorrhagic Fever]
Venezuelan Hemorrhagic Fever

Guanarito Hemorrhagic Fever

Vehf - [Venezuelan Haemorrhagic Fever]
Brazilian Hemorrhagic Fever

Sabia Hemorrhagic Fever
Ebola Hemorrhagic Fever

Ebola Virus Disease

Viral Hemorrhagic Fever

Hemorrhagic Fever, Ebola

Ebola

Ehf

Ebola Fever

Hemorrhagic Fevers, Viral

Ebola Haemorrhagic Fever

Ebod - [Ebola Disease]

Evd - [Ebola Virus Disease]

Ebola Virus Haemorrhagic Fever

Vhf - [Viral Haemorrhagic Fever] Nos

Viral Haemorrhagic Fever, Not Otherwise Specified
Lassa Fever

Lf

Lassa Hemorrhagic Fever

Lf - [Lassa Fever]
Lujo Hemorrhagic Fever

Zambian Hemorrhagic Fever
Klippel-Feil Syndrome 4
Blessig'S Cysts

Microcystoid Retinal Degeneration

Blessig Cysts

Iwanoff'S Cysts

Microcystoid Degeneration Of Retina
De Quervain Disease

Radial Styloid Tenosynovitis

Tenosynovitis, De Quervain'S

De Quervain'S Disease

Tenosynovitis Of Radial Styloid Process

Stenosans Tenosynovitis
Immature Cataract

Incipient Cataract

Incipient Senile Cataract

Water Clefts
Crimean-Congo Hemorrhagic Fever

Crimean Hemorrhagic Fever

Cchf

Congo Hemorrhagic Fever

Hemorrhagic Fever, Crimean

Chf Congo Virus

Congo-Crimean Hemorrhagic Fever

Congo Fever

Hemorrhagic Fever Crimean-Congo

Cchf - [Crimean-Congo Haemorrhagic Fever]

Kara Mikh Typhoid Fever

Xīnjiāng Haemorrhagic Fever
Hemochromatosis, Type 1

Hemochromatosis

Hemochromatosis Type 1

Hereditary Hemochromatosis

Hh

HFE1

Hfe Hemochromatosis, Modifier Of

Symptomatic Form Of Classic Hemochromatosis

Symptomatic Form Of Hemochromatosis Type 1

Symptomatic Form Of Hfe-Related Hereditary Hemochromatosis

Haemochromatosis

Iron Storage Disorder

Bronze Diabetes

Hereditary Haemochromatosis

Hlah

Hfe

Hemochromatosis, Hereditary

Diabetes Bronze

Classic Hemochromatosis

Hfe-Associated Hereditary Hemochromatosis

Hemochromatosis Classic

Bronzed Cirrhosis

Familial Hemochromatosis

Genetic Hemochromatosis

Hc

Pigmentary Cirrhosis

Primary Hemochromatosis

Troisier-Hanot-Chauffard Syndrome

Von Recklenhausen-Applebaum Disease

Hemochromatosis 1

Primary Hereditary Hemochromatosis

Bronze Cirrhosis
Stuttering

Stammering

Familial Persistent Stuttering

Stuttering, Familial Persistent 1
Niemann-Pick Disease, Type C1

Niemann-Pick Disease, Type C

NPC1

Niemann-Pick Disease, Type D

Niemann-Pick Disease Type C1

Niemann-Pick Disease With Cholesterol Esterification Block

Niemann-Pick Disease, Subacute Juvenile Form

Neurovisceral Storage Disease With Vertical Supranuclear Ophthalmoplegia

Npc

Niemann-Pick Disease, Chronic Neuronopathic Form

Niemann-Pick Disease Without Sphingomyelinase Deficiency

Niemann-Pick Disease Type C

Niemann-Pick Disease Type D

Niemann-Pick C1 Disease

Niemann-Pick Disease C1

Niemann-Pick Disease Chronic Neuronopathic Form

Niemann-Pick Disease Nova Scotian Type

Niemann-Pick Disease Subacute Juvenile Form

Niemann-Pick Disease Type Ii

Niemann-Picks Disease Type C
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05908 GTPBP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus GTPBP1 VGNC VGNC:67507
Mus musculus GTPBP1 MGD MGI:109443
Rattus norvegicus GTPBP1 RGD RGD:1306758
Canis familiaris GTPBP1 VGNC VGNC:41557
Bos taurus GTPBP1 VGNC VGNC:29708
Macaca mulatta GTPBP1 VGNC VGNC:73320
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